Results 51 to 60 of about 282,361 (265)

Dynamics of Local Government Policies in Providing Recognition and Protection of Customary Law Communities in Maluku

open access: yesJurnal Penelitian Hukum De Jure, 2023
The problem of protecting and recognizing the rights of Customary Law Communities in Indonesia, including in Maluku, from the perspective of local government policies, is still being underestimated, even though Article 18 B paragraph (2) of the ...
Nasaruddin Umar   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Alberta’s 2002 Teacher Strike: The Political Economy of Labor Relations in Education La huelga de profesores de Alberta en 2002. La economía política de las relaciones laborales en el sector de educación A greve de professores de Alberta em 2002. A economia política das relações de trabalho no setor da educação

open access: yesEducation Policy Analysis Archives, 2010
In 2002, approximately two thirds of school teachers in the Canadian province of Alberta went on strike. Drawing on media, government and union documents, this case study reveals some contours of the political economy of labor relations in education that
Bob Barnetson
doaj  

Unlocking value: a comprehensive costing study of primary health care service delivery in Tanzania

open access: yesBMC Primary Care
Background Tanzania has long prioritized primary health care (PHC) as the pathway to achieving universal health coverage. However, greater, and more effective investments are needed to expand access to quality PHC services and further improve population ...
Federica Margini   +8 more
doaj   +1 more source

DESAIN OTONOMI DAERAH DALAM KERANGKA PENEGASAN SISTEM PEMERINTAHAN PRESIDENSIAL

open access: yesProgresif, 2019
This research is entitled “Design Of Regional Autonomy In The Affirmative Framewok Of Presidential Government Systems Affirmation:. This research is motivated by the decentralization of Indonesia which has unsymmetrical, because of the existence of ...
Rio Armanda Agustian
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Bronchoscopic management of near-complete malignant tracheal obstruction secondary to recurrent papillary thyroid carcinoma using multimodality therapeutic bronchoscopy – a case report

open access: yesThe Egyptian Journal of Bronchology
Background Papillary thyroid carcinoma has a favorable prognosis; however, recurrent or locally invasive disease may rarely involve the trachea and cause critical airway obstruction.
Hadi Mohammed Abdullah   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Leadership and governance in regional tourism [PDF]

open access: yesJournal of Destination Marketing & Management, 2015
The rise of neoliberal market management has contributed to an incontrovertible “truth” that regional tourism organizations (RTOs) established and led by business actors are more effective in leading regional tourism development. Despite these assertions, little evidence has surfaced to support the idea that market-led governance offers a superior ...
Flávio Valente   +2 more
openaire   +2 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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