OBJETIVO: El Instituto Mesoamericano de Salud Pública (IMSP) se constituyó en 2009 como órgano técnico del Sistema Mesoamericano de Salud Pública (SMSP) y la Red Virtual de Instituciones Académicas.
Miguel A González-Block+3 more
doaj
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song+24 more
wiley +1 more source
Perspectivas de região e redes na política de saúde brasileira
Regiões e Redes de Atenção à Saúde são estratégias recentes da política de saúde brasileira. Questiona-se: quais concepções de região e redes de saúde informam a política, como se combinam, em que momentos e com quais objetivos?
Mariana Vercesi de Albuquerque+1 more
doaj +1 more source
Mental health plans and policies across the WHO European region
Abstract Evidence is scarce in terms of tracking the progress of implementation of mental healthcare plans and policies (MHPPs) in Europe, we aimed to map and analyze the content of MHPPs across the WHO European region. We collected data from the WHO Mental Health Atlas 2011, 2017 and 2020 to map the development of MHPPs in the region.
Zoe Guerrero+10 more
openaire +3 more sources
European Public Health News * EUPHA President's column * EUPHA office news * Message from the Regional Director (January 2013)--A Historical Turning Point to Fight Antibiotic Resistance * Increasing Efforts on Vaccine Preventable Diseases in the EU * Three Priorities of the 2013 Work Plan of ECDC * 6TH European Public Health Conference--Health in Europe: Are we there Yet? Learning from the Past, Building the Future [PDF]
Dineke Zeegers Paget+5 more
openalex +1 more source
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang+8 more
wiley +1 more source
Analisis Hierarki Wilayah Dan Interaksi Wilayah Untuk Penentuan Pusat Pelayanan Wilayah Di Kabupaten Lembata Provinsi Nusa Tenggara Timur [PDF]
Lembata Regency is one of the districts that are categorized as underdeveloped areas and has unique characteristics because it has administrative areas with island characteristics. Spatial structure in the district with characteristics of areas that have
, Drs. Priyono, Pratama, Bruce
core
Waste indicators of primary sector and health & veterinary services for regional planning [PDF]
Eva Cifrián+4 more
openalex +1 more source
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan+14 more
wiley +1 more source
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich+8 more
wiley +1 more source