Results 41 to 50 of about 1,165,606 (291)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Understanding the Narratives Explaining the Ukrainian Crisis: Identity Divisions and Complex Diversity in Ukraine

open access: yesActa Universitatis Sapientiae: European and Regional Studies, 2017
The central argument of this paper is that radical and opposing interpretations of the Ukrainian conflict in politics and media should be studied as offspring of broader narratives.
Smoor Lodewijk
doaj   +1 more source

The Effects of English Language Learning on the Perception and Value of Regional and National Identity in Colombia.

open access: yesIkala: Revista de Lenguaje y Cultura, 2018
There exist many popular ideas as to the supposed negative effects of English as a foreign language (EFL) education on local and national identities in Colombia, and this study examines whether there is any truth to such claims.
Joshua James Zwisler
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The Politics of Spatial Identity: Regional Governance and the Strategic Constitution of Regional Identity

open access: yesNordia Geographical Publications, 2007
Recent German planning discourse focuses on major urban agglomerations and their role for societal, economic, social and cultural development. Of special interest are questions concerning the European Metropolitan Regions. Seen as an effective concept of
Tobias Federwisch
doaj  

Regional Identity and Multiculturalism: the Baltic Germans of Latgale in the Early 20th Century Latvian Literature

open access: yesRespectus Philologicus, 2021
In the studies of Latvian culture and history, there is a number of investigations dedicated to the influence of Baltic German culture on Latvian culture. Hence the Latgale region was not given due attention in this regard. The role of the Baltic Germans
Alina Romanovska
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Creativity of Regionalisms on the Level of Word Building

open access: yesФилологический класс, 2022
The article deals with the peculiarities of creating and functioning of regionalisms: regional words and word combinations used by the residents of a certain region.
doaj   +1 more source

Places/Non-Places: Galicia on the \u3cem\u3eRoad of St. James\u3c/em\u3e [PDF]

open access: yes, 2017
This chapter offers a critical reconsideration of the theory according to which the Road of St. James (Camiño de Santiago) provides a site for ethnic identity-making capable of modernizing Galicia as a rural region.
Afinoguénova, Eugenia
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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