Results 41 to 50 of about 1,352,266 (328)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Do it together! Conception and long-term results of the trans-institutional Master of Medical Education (MME) program in Germany

GMS Journal for Medical Education, 2020
Medical education has the responsibility to react to developments and changing demands in healthcare. This implies the need for experts in the area of medical education as well as nationally coordinated initiatives.
Jünger, Jana, Pante, Saskia V., Ackel-Eisnach, Kristina, Wagener, Stefan, Fischer, Martin R.   +4 more
doaj   +1 more source

Implementing Caregiver Support Programs in a Regional Stroke System.

Stroke, 2019
Background and Purpose- Family caregivers play a central role in the recovery of people with stroke. They need support to optimize the care they provide and their own health and well-being.
V. Tseung, S. Jaglal, N. Salbach, J. Cameron   +3 more
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Regional Coalitions for Healthcare Improvement: Definition, Lessons, and Prospects [PDF]

, 2006
Outlines how regional quality coalitions can collaborate to help deliver evidence-based healthcare; improve care processes; and measure, report, and reward results.
Barbra G. Rabson, Gordon Mosser, Melinda Karp   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Connecting the Dots: A Healthy Community Leader's Guide to Understanding the Nonprofit Hospital Community Benefit Requirements [PDF]

, 2015
Imagine a healthy community as a connect-the-dots landscape painting. Each "dot" has its place and purpose: affordable housing, a vibrant economy, safe streets and public transportation, a high quality public education system, easy access to fresh food ...
C. J. Eisenbarth Hager
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Export of Medical Services in the Tyumen Region: Nosological Analysis for 2023

Здоровье мегаполиса
Introduction. Since 2019, the export of Russian medical services has been realized in accordance with the “Development of the export of medical services” regional project that is being implemented in 70 subjects of the Russian Federation. This initiative
О. S. Chernova, G. D. Petrova
doaj   +1 more source

Creating Community Environments That Promote Comprehensive Health and Wellness [PDF]

, 2006
Describes the impact of Hurricanes Katrina and Rita on the health of the residents of Arkansas, Louisiana, and Mississippi. Outlines strategies to identify effective programs designed to reduce health disparities and improve health status in the ...

core