A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
A ROADMAP FOR A NEW MINDSET IN REGIONAL SCIENCE: THE REGIONAL SCIENCE ACADEMY
, 2015 This contribution argues that the great many spatial challenges of our world and the emerging spatial dynamics call for new modes of thinking on regional science research. The creation of a Regional Science Academy may be helpful in meeting this novel demand.
Kourtit, Karima +2 more
openaire +1 more source
, 2018 Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services
openalex +2 more sources
Abstracts of Presentations from the 2019 Regional Meetings of the American Society for Horticultural Science [PDF]
, 2019 Jan Baldwin +99 more
openalex +1 more source
The Dynamics of Economic Policy and Regional Specialization: Evidence from China¡¯s High-tech Industry [PDF]
: This paper investigates the effects of economic policy on regional specialization of China¡¯s high-tech industries for the period 1996 to 2005. Results indicate that the average level of regional specialization increases over years.
Dan Zheng
core
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
The Impact of the Depth of Technology Transfer Type Provisions in Regional Trade Agreements on International Science and Technology Cooperation - An Empirical Study Based on RCEP Member Countries [PDF]
Yanlin Sun, Linli Li
openalex +1 more source
A first assessment of operator compliance and dolphin behavioural responses during swim-with-dolphin programs for three species of Delphinids in the Azores [PDF]
, 2019 The popularity of swim-with wild dolphin programs around the world is fast growing, with the studies required to investigate their impact lagging behind. In the Azores, species targeted include the short-beaked common (Delphinus delphis), the bottlenose (
Azevedo, José M. N. +3 more
core
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source