Results 281 to 290 of about 8,931,171 (392)

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

open access: yesAdvanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk   +6 more
wiley   +1 more source

Trends and factors associated with pneumonia mortality at Buea Regional Hospital in Cameroon from 2020 to 2023. [PDF]

open access: yesPLoS One
Tufon KA   +10 more
europepmc   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel   +6 more
wiley   +1 more source

A Patient‐Specific 3D Printed Carotid Artery Model Integrating Vascular Structure, Flow, and Endothelium Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces the first miniaturized, patient‐specific carotid artery model created via 3D printing using GelMA with embedded vascular cells. Combining CFD, PIV, and flow perfusion, the model replicates anatomically dependent hemodynamics and cellular responses.
Jorge A. Catano   +7 more
wiley   +1 more source

Learning approaches in students of the areas of Health Sciences belonging to a regional university in Chile

open access: diamond
Mónica Cardona Valencia   +4 more
openalex   +2 more sources

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

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