Results 141 to 150 of about 26,753 (310)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Scanians, Scania and Scanialand − Ethnic Problems and Regionalisation in Northern Europe

open access: yesMigracijske i etničke teme, 1998
Scania and Scanialand have been subject to diverse fates. From being the original home of the Lombards (Langobards) via the core of the Danish realm to a province in the periphery of Sweden from 1658.
Bertil Haggman
doaj  

South-East Region in Bulgaria: Economic Performance and Key Sectors Analysis [PDF]

open access: yes
The present paper attempts to provide insight into the economic performance of the South-east region (SER) of Bulgaria by presenting quantitative relationships between sectors in the regional economy.
Antoaneta GOLEMANOVA
core  

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink   +3 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Cortical bone porosity is spatially heterogeneous and VEGF dependent in male bone. [PDF]

open access: yesDis Model Mech
Trend J   +8 more
europepmc   +1 more source

The structural transition of the production system: Regional policy in common understanding [PDF]

open access: yes
Several scientists, politicians are perceiving a fundamental shift in the structure of the production process and the political regulation-system governing that process.
Carl Devos
core  

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