Results 111 to 120 of about 670,351 (340)
Characterization of the frequency of extreme events by the Generalized Pareto Distribution
Based on recent results in extreme value theory, we use a new technique for the statistical estimation of distribution tails. Specifically, we use the Gnedenko-Pickands-Balkema-de Haan theorem, which gives a natural limit law for peak-over-threshold ...
Pisarenko, V. F., Sornette, D.
core +1 more source
Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta +18 more
wiley +1 more source
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
ANALYSIS OF THE EFFECTS IN ITALY OF ALTERNATIVE HYPOTHESES OF REGIONALIZATION OF THE SINGLE PAYMENT SCHEME [PDF]
The Fischler reform of the CAP deepened the decoupling process of agricultural support started with the 1992 reform, introducing the Single Payment Scheme (SPS).
Pupo D'Andrea, Maria Rosaria
core +1 more source
NAFTA: Will it ever have an EU profile? Jean Monnet/Robert Schuman Paper Series Vol. 7 No. 3 April 2007 [PDF]
[Introduction]. Based on the experiences of regionalization and integration processes, this paper identifies the main transformations North America has undergone as a result of the implementation of NAFTA. The main argument is that the operation of NAFTA
Dominguez, Roberto.
core
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
A simple qualitative approach for mapping regional landslide susceptibility in the Faroe Islands [PDF]
Mette Dahl +3 more
openalex +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Family names as indicators of Britain’s changing regional geography [PDF]
In recent years the geography of surnames has become increasingly researched in genetics, epidemiology, linguistics and geography. Surnames provide a useful data source for the analysis of population structure, migrations, genetic relationships and ...
Cheshire, JA, Longley, PA, Mateos, P
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