Results 111 to 120 of about 1,669,450 (308)

Borders matter!: Regional integration in Europe and North America [PDF]

open access: yes
We analyze the spatial interaction among regions in North America and in Western Europe. We use a gravity model extended by a spatial correlation structures where data allows to evaluate the level of impact and the length of the spatial tail. This allows
Blum, Ulrich
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The Impact of European Institutions on Local and Regional Development

open access: yesEIRP Proceedings, 2019
A united Europe is the sum up of how different regions live together and find common perspectives. This does not fit only as a political, social or philosophical idea, but since the creation of the European Union, regional development remains one of ...
Olta Qejvani, Brikena Buda (Dhuli)
doaj  

Educational Differences in Cohort Fertility Across Sub-national Regions in Europe. [PDF]

open access: yesEur J Popul, 2021
Nisén J   +16 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A ‘Europe of the Regions’ – Swedish Regions as the Undead

open access: yesL'Europe en Formation, 2016
Le débat sur l’Europe des régions à la fin des années 1980 et au début des années 1990 a influencé le processus de régionalisation suédois en cours ; les acteurs régionaux l’ont utilisé comme un argument pour une plus grande décentralisation du pouvoir, avec un certain succès (Warleigh-Lack & Stegmann McCallion 2012).
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Labor productivity in Europe: Evidence from a sample of regions [PDF]

open access: yes
The present paper aims at analyzing the sources of productivity in Europe to account for its recent underperformance and identify potential geographic idiosyncracies.
Lionel Artige, Rosella Nicolini
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

How to Protect Natural Habitats of Rare Terrestrial Orchids Effectively: A Comparative Case Study of Cypripedium calceolus in Different Geographical Regions of Europe. [PDF]

open access: yesPlants (Basel), 2021
Jakubska-Busse A   +10 more
europepmc   +1 more source

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