Results 51 to 60 of about 1,669,450 (308)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The Kallikrates vs the Kapodistrias Reforms in Greece: A Story of Moderate Success

Politics in Central Europe, 2018
This article aims to analyse and evaluate the implementation of Greek local government reforms based on the surrounding economic and political situation.
Kalimeri Vasiliki
doaj   +1 more source

Mutual conditioning of factors of regional economic integration in Europe [PDF]

Anali Ekonomskog fakulteta u Subotici, 2020
This paper looks into one of the basic theoretical concepts of mutual cooperation of regions in Europe, known as the concept of Europe of the Regions. Through it could be observed the influence of non-economic as well as economic factors participating in
Srzentić Miloš
doaj  

Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina: the EuroSIDA study [PDF]

, 2012
BACKGROUND Differences in access to care and treatment have been reported in Eastern Europe, a region with one of the fastest growing HIV epidemics, compared to the rest of Europe.
Antonucci G., Antunes F., Arici C., Bakowska E., Banhegyi D., Barton S., Battegay M., Begovac J., Benfield T., Beniowski M., Boffi E., Bogner J., Boron-Kaczmarska A., Bravo I., Bruun J., Burger D., Burke M., Buzunova S., Caldeira L., Castagna A., Chaplinskas S., Chentsova N., Chirianni A., Clotet B., Clumeck N., Colebunders R., Cozzi-Lepri A., D'Arminio Monforte A., Dabis F., De Wit S., Degen O., Delforge M., DeWitt S., Domingo P., Doroana M., Duiculescu D., Elias C., Ellefson M., Elzi L., Esposito R., Fatkenheuer G., Filandras A., Fischer A. H., Fisher M., Flamholc L., Flisiak R., Francioli P., Frolov V., Furrer H., Gabbuti A., Galli M., Gargalianos P., Gargiulo M., Gasiorowski J., Gatell J., Gatell J. M., Gazzard B., Gerstoft J., Gianotti N., Girard P. -M., Gonzalez-Lahoz J., Grarup J., Grint D., Grzeszczuk A., Gutierrez M., Hadziosmanovic V., Hansen A. -B. E., Hassoun G., Hemmer R., Hirschel B., Horban A., Jablonowska E., Jevtovic D., Jilich D., Johnson A. M., Johnson M. A., Jou A., Karabatsaki E., Karlsson A., Karlsson A., Karpov I., Katlama C., Katzenstein T., Kirk O., Kjaer J., Knysz B., Kosmidis J., Kostov K., Kowalska J. D., Krasnov M., Kravchenko E., Kronborg G., Kutsyna G., Labarga P., Larsen M., Lazzarin A., Ledergerber B., Leen C., Lichtner M., Livrozet J. M., Losso M., Lundgren J. D., Maayan S., Machala L., Maeland A., Malolepsza E., Maltez F., Mansinho K., Mateo G., Mazeu I., Mazzotta F., Medrano J., Mercey D., Miro J. M., Mitsura V. M., Mocroft A., Mokras M., Montesarchio E., Moreno S., Mularska E., Mulcahy F., Murphy M., Mussini C., Narciso P., Neau D., Nielsen J., Ormaasen V., Ostergaard L., Panos G., Parczewski M., Paredes R., Pedersen C., Perdios J., Peters L., Phillips A., Podlekareva D., Pollack S., Pradier C., Pristera R., Puig J., Pynka M., Rakhmanova A., Reekie J., Reiss P., Ridolfo A., Ristola M., Rockstroh J., Rodriguez J. M., Rozentale B., Sambatakou H., Sambeat M. A., Schmidt R., Scullard G., Sedlacek D., Servitskiy S., Skinhoj P., Smidt J., Soriano V., Stanekova D., Staszewski S., Staub T., Stellbrink H. J., Suetnov O., Testa A., Thiebaut R., Tomazic J., Trocha H., Tural C., Turner D., Tverland J., Van Lunzen J., Vandekerckhove L., Vanhems P., Vassilenko A., Vella S., Vetter N., Viard J. -P., Vlassi C., Vullo V., Weber J., Weber R., Wojcik K., Xylomenos G., Yust I., Zaccarelli M., Zakharova N., Zangerle R., Zeltina I., Zilmer K.   +188 more
core   +7 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Success factors of international sporting events in different regions of Europe

Apstract: Applied Studies in Agribusiness and Commerce, 2013
Sport events always played an important role in human life from the ancient Olympics and marathon races to today’s modern Olympics, World and continental championships.
Gabriella Cserháti, Réka Polák-Weldon   +1 more
doaj   +1 more source

Genetic diversity of the cestode Echinococcus multilocularis in red foxes at a continental scale in Europe. [PDF]

PLoS Neglected Tropical Diseases, 2009
Alveolar echinococcosis (AE) is a severe helminth disease affecting humans, which is caused by the fox tapeworm Echinococcus multilocularis. AE represents a serious public health issue in larger regions of China, Siberia, and other regions in Asia.
Jenny Knapp, Jean-Mathieu Bart, Patrick Giraudoux, Marie-Louise Glowatzki, Isabelle Breyer, Francis Raoul, Peter Deplazes, Georg Duscher, Karel Martinek, Pavol Dubinsky, Marie-Hélène Guislain, Florence Cliquet, Thomas Romig, Andrzej Malczewski, Bruno Gottstein, Renaud Piarroux   +15 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Technological Advantages of the Regions of Central and Eastern Europe

Problemy Zarządzania, 2016
This paper takes up the problem of the potential technological advantages of the economies of the regions of Central and Eastern Europe. An answer to the question of the directions and change dynamics of technology in the regions of countries that ...
Rafał Wisła
doaj   +1 more source