Results 71 to 80 of about 1,669,450 (308)
The role of the regions in border dynamics in Europe [PDF]
Revista CIDOB d'Afers Internacionals, 2005 This article analyses the role that the regions have played during this past half century, and which they continue to play now, in the changes that are occurring along the borders between European states and in the webs of interests that are woven as a ...
Desiderio Fernández Manjón
doaj
Spatial reconfiguration and problems of governance in urban regions of Europe
Belgeo, 2007 Since the 1980s under the challenges of globalisation, de-industrialisation and tertiarisation European urban regions are changing their traditional urban fabric and pattern and their economic orientation.
Axel Borsdorf, Willem Salet
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Delimiting Central Europe as a Juridical Space: A Preliminary Exercise in Critical Legal Geography
Acta Universitatis Lodziensis Folia Iuridica, 2019 The aim of the present paper is to contribute to the on-going discussion, both in legal theory and in comparative law, concerning the status of Central Europe and its delimitation from other legal regions in Europe, notably Romano-Germanic Western Europe
Rafał Mańko
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Interrelationships and Causal Linkages Between Socioeconomic and Environmental Factors [PDF]
The purpose of this study was to examine interrelationship and causal linkages between socioeconomic and environmental variables in OECD countries. To aid this study, a LISREL modelling tool was implemented. The findings of the study indicated that gross
Barre, Mike +3 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Studia Universitatis Babeş-Bolyai. Studia Europaea, 2018 The present article deals with forms of cross-border co-operation that were established along the Dutch-German borders since the 1950s. They were testing grounds for new regional forms of governance and consolidated as one level within the European ...
Claudia HIEPEL
doaj +1 more source
A Europe of the Regions vs. the Regions in Europe: Reflections on Regional Engagement in Brussels [PDF]
Regional & Federal Studies, 2008 Analysis of regional representation in the EU today provides us with something of a paradox. Whilst the idea of a Europe of the Regions replacing a state-centred EU has been marginalized in mainstream political thought, regional actors continue to strengthen their engagement with European affairs and to challenge central state authority directly in the
openaire +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
What Europe? Fortress, different speeds, coloniser or archipelago [PDF]
The paper starts with the introduction of a simple analytical tool that classifies regions according to their scale and accessibility. Those indicators are closely related to the strategies of European expansion and European integration and at the same ...
Tomaz Ponce Dentinho
core