Results 191 to 200 of about 429,858 (263)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Child-Directed Speech Facilitates Semantic Role Learning: A Machine Learning Approach. [PDF]

Open Mind (Camb)
Huber E, Bickel B, Stoll S.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Palliative care beyond traditional boundaries: A nationwide survey of bereavement support in the form of conversations and Palliative Care Registry utilization at Swedish stroke units. [PDF]

Palliat Care Soc Pract
Mårtensson S, Rejnö Å.
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Concordance of positive, negative and disorganised psychotic syndromes in five twin samples. [PDF]

BJPsych Open
Cardno AG, Marshall EJ, Toulopoulou T, Kravariti E, Pepper EJ, Rijsdijk FV, Allardyce J, Murray RM, Vassos E.   +8 more
europepmc   +1 more source

Cognitive ability following exposure to parental mental disorders and other childhood adversities: a population-based cohort study of Danish males in late adolescence. [PDF]

Eur J Pediatr
Petersen TG, Okholm GT, Davidsen K, Wesselhoeft R, Osler M, Munk-Olsen T, Bliddal M.   +6 more
europepmc   +1 more source

Trends in antipsychotic drug utilisation and indication in the paediatric population: a nationwide cohort study in Sweden. [PDF]

BMJ Ment Health
S Kamgang KH, Pasternak B, Reutfors J, Pradhan R, Wintzell V.   +4 more
europepmc   +1 more source

Correction: Real-world sex differences in treatment persistence and reasons for discontinuation in psoriatic arthritis patients: results from the German RABBIT-SpA register. [PDF]

Arthritis Res Ther
Lindner L, Weiß A, Reich A, Baumann C, Behrens F, Baraliakos X, Regierer AC.   +6 more
europepmc   +1 more source