Results 111 to 120 of about 51,772 (234)

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

open access: yesChemistry – A European Journal, EarlyView.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere   +2 more
wiley   +1 more source

Visual content and thematic analyses of images shared on social media before and after episodes of self-harm in a UK clinical youth sample. [PDF]

open access: yesBMJ Open
Bye A   +7 more
europepmc   +1 more source

Exploring communication preferences of trans and gender diverse individuals-A qualitative study. [PDF]

open access: yesPLoS One, 2023
von der Warth R   +3 more
europepmc   +1 more source

Design and implementation of a 3D‐printed modular distillation tower for experimental teaching in chemical engineering

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Several authors have reported the disconnection between the skills, abilities, and attitudes of graduates from STEM careers with the current needs of the labour market. In science and engineering fields, research has found the need for interdisciplinary approaches that encourage meaningful learning.
Úrsula Manríquez‐Tolsá   +7 more
wiley   +1 more source

Identifying potential key metabolic pathways and biomarkers in glaucoma: a systematic review and meta-analysis. [PDF]

open access: yesBMJ Open Ophthalmol
Golpour N   +6 more
europepmc   +1 more source

Development and Retrospective Application of Novel Outcome Measure: Sturge–Weber Syndrome Acute Crisis (SWAC) Index

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Sturge–Weber syndrome (SWS) symptoms frequently overlap in neurological acute crises (ACs) presenting with seizures, stroke‐like episodes (SLE), and headaches. Recent efforts to develop a prospective drug trial highlighted the need for a new outcome measure capable of quantifying these symptoms during an SWS AC.
Kieran D. McKenney   +3 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

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