Results 41 to 50 of about 51,772 (234)

Irony's architecture: Reflections on a photographic research project [PDF]

, 2007
This paper presents a research approach based on irony, rather than certainty. Using Richard Rorty's conception of irony, we contend that much traditional research in management presents a final language which is implicit in both the construction of a ...
Bathurst, Ralph, Sayers, Janet, Symonds, Henry   +2 more
core   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Researching in-between experience and reality [PDF]

, 2012
In this article, we draw on LORENZER's method in our analysis of a single case data extract derived from a research project generating data through the Tavistock Infant Observation tradition.
Froggett, Lynn, Holloway, Wendy
core  

Teaching archive skills: a pedagogical journey with impact [PDF]

, 2020
This article considers the pedagogical practice of the Special Collections staff team at the University of Sussex and the impact of the group visit experience on student learning.
Pattrick, Kirsty, Watson, Karen
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

Advanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang, Xuedong Wang, Mengyao Wang, Qian Zhou, Lusheng Wang, Shuai Cheng Li   +5 more
wiley   +1 more source

Posing as the ultimate Scottish Songster: James Hogg’s Songs by the Ettrick Shepherd or Hogg GOLD! [PDF]

, 2011
A brief article about the completion of the AHRC-funded James Hogg Songs Project and the place of Hogg's final collection of songs in his work and ...
McCue, Kirsteen
core  

No good surprises: intending lecturers' preconceptions and initial experiences of further education [PDF]

, 2002
Current initiatives to promote lifelong learning and a broader inclusiveness in post-16 education have focused attention on further education (FE). The article examines the experiences and reactions of 41 intending lecturers studying full-time for a ...
AlNLEY P., BALL S., BALL S., BANKS I., BLUNKETT D., BREAN S., CAMPBELL J., DEARING R., DELAMONT S., DEPARTMENT FOR EDUCATION &, DEPARTMENT FOR EDUCATION AND EMPLOYMENT, ECO U., FURTHER EDUCATION NATIONAL TRAINING ORGANISATION (FENTO), GOODSON I., LYOTARD J-F., MORAN A., REEVES F., ROGERS C., SHERMAN R., Sue Wallace, WATSON R.   +20 more
core   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source