Results 1 to 10 of about 70,656 (199)

Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis: A European Multicenter Observational Study. [PDF]

Arthritis Rheumatol, 2022
Objective Mepolizumab proved to be an efficacious treatment for eosinophilic granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the randomized, controlled MIRRA trial. In a few recently reported studies, successful real‐life experiences with the approved dose for treating severe eosinophilic asthma (100 mg every 4 weeks) were ...
Bettiol A, Urban ML, Dagna L, Cottin V, Franceschini F, Del Giacco S, Schiavon F, Neumann T, Lopalco G, Novikov P, Baldini C, Lombardi C, Berti A, Alberici F, Folci M, Negrini S, Sinico RA, Quartuccio L, Lunardi C, Parronchi P, Moosig F, Espígol-Frigolé G, Schroeder J, Kernder AL, Monti S, Silvagni E, Crimi C, Cinetto F, Fraticelli P, Roccatello D, Vacca A, Mohammad AJ, Hellmich B, Samson M, Bargagli E, Cohen Tervaert JW, Ribi C, Fiori D, Bello F, Fagni F, Moroni L, Ramirez GA, Nasser M, Marvisi C, Toniati P, Firinu D, Padoan R, Egan A, Seeliger B, Iannone F, Salvarani C, Jayne D, Prisco D, Vaglio A, Emmi G, European EGPA Study Group.   +55 more
europepmc   +2 more sources

Overlapping forms of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis: Insights from a European multicenter study. [PDF]

J Intern Med
Abstract Background Granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) are distinct forms of antineutrophil cytoplasm antibody (ANCA)‐associated vasculitis (AAV). Increasing evidence suggests overlapping features, particularly in proteinase 3 (PR3)‐ANCA‐positive EGPA and GPA with eosinophilia.
Pallotti F, Mettler C, Papo M, Iudici M, Padoan R, Sorin B, Regola F, Franceschini F, Moiseev S, Novikov P, Piga MA, Moroncini G, Brix SR, Kafagi AH, Deshayes S, Aouba A, Campagne J, Delvino P, Tervaert JWC, Brussino L, Michaud M, Venhoff N, Alberici F, Iannone C, Rosenstingl S, Moutel M, Galempoix JM, Cottin V, Jaccard C, Riehl D, Legendre P, Billet AC, Parronchi P, Quartuccio L, Teixeira V, Egan A, Jayne D, Tombetti E, Caminati M, Pagnoux C, Regent A, Ruivard M, Guillevin L, Puéchal X, Terrier B, French Vasculitis Study Group (FVSG).   +45 more
europepmc   +2 more sources

Novel Therapies in Takayasu Arteritis [PDF]

Frontiers in Medicine, 2022
Takayasu Arteritis (TAK) is a large-vessel vasculitis that preferentially involves the aorta and its primary branches. Cardiac involvement is frequent in TAK and is a major determinant of the patient's outcome.
Francesca Regola, Francesca Regola, Martina Uzzo, Martina Uzzo, Paola Toniati, Barbara Trezzi, Barbara Trezzi, Renato Alberto Sinico, Renato Alberto Sinico, Franco Franceschini, Franco Franceschini   +10 more
doaj   +2 more sources

Novel Targets for Drug Use in Eosinophilic Granulomatosis With Polyangiitis [PDF]

Frontiers in Medicine, 2021
Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare autoimmune disease characterized by medium and small vessels inflammation. Cardiac vasculitic involvement is one of the most severe manifestations with a significant impact on patients' long ...
Martina Uzzo, Martina Uzzo, Francesca Regola, Francesca Regola, Barbara Trezzi, Barbara Trezzi, Paola Toniati, Franco Franceschini, Franco Franceschini, Renato Alberto Sinico, Renato Alberto Sinico   +10 more
doaj   +2 more sources

Materiali sonori e regola percettiva

Rivista di Estetica, 2017
The topic of analogical relationship between hearing and meaning has strong repercussions in the history of musical understanding. The high-low couple, the ground of spatial dimension in music, turns in a lot of metaphorical meanings which show the way ...
Carlo Serra
doaj   +4 more sources

Storing and Using Health Data in a Virtual Private Cloud

Journal of Medical Internet Research, 2013
Electronic health records are being adopted at a rapid rate due to increased funding from the US federal government. Health data provide the opportunity to identify possible improvements in health care delivery by applying data mining and statistical ...
Regola, Nathan, Chawla, Nitesh V
doaj   +2 more sources

Association Between Changes in BLyS Levels and the Composition of B and T Cell Compartments in Patients With Refractory Systemic Lupus Erythematosus Treated With Belimumab [PDF]

Frontiers in Pharmacology, 2019
Introduction: Belimumab is a monoclonal antibody against soluble BLyS used for treatment of refractory Systemic Lupus Erythematosus (SLE). Although B cells are the main target of this therapy, a BLyS-dependent T cell activation pathway has also been ...
Francesca Regola, Francesca Regola, Silvia Piantoni, Silvia Piantoni, Torsten Lowin, Silvia Archetti, Rossella Reggia, Rajesh Kumar, Franco Franceschini, Franco Franceschini, Paolo Airò, Angela Tincani, Angela Tincani, Laura Andreoli, Laura Andreoli, Georg Pongratz   +15 more
doaj   +2 more sources

Effects of warming temperatures on germination responses and trade‐offs between seed traits in an alpine plant

Journal of Ecology, Volume 111, Issue 1, Page 62-76, January 2023., 2023
Our study shows the importance of growth conditions when evaluating the seed size versus number trade‐off. Stressful conditions, such as warmer temperatures, can restrain the ability of plants to reach optimal investment in reproduction, masking the trade‐off.
Rocco F. Notarnicola, Adrienne B. Nicotra, Loeske E. B. Kruuk, Pieter A. Arnold   +3 more
wiley   +1 more source

A visual testament by Luca Riva, a deaf and mute pupil of the Procaccini

Renaissance Studies, Volume 36, Issue 2, Page 222-251, April 2022., 2022
Abstract The paper investigates the visual testament by Luca Riva, a mute and deaf artist who studied in Milan under Camillo Procaccini. Dated 9 September 1624, the document consists of twelve folios bound together in a small volume. On the sheets, ten brown‐ink drawings illustrate the beneficiaries of Riva’s testament, identifying the inheritance ...
Angelo Lo Conte
wiley   +1 more source

Un grafo per il “Furioso”. Prime annotazioni di una ricerca sperimentale

AOQU, 2022
Sulla scorta delle precedenti ricerche condotte da Franco Moretti e Michal Ginsburg, in questo contributo i mezzi della social network analysis vengono sperimentalmente applicati allo studio della trama dell’Orlando furioso.
Gaudenzia Genoni
doaj   +1 more source