Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis: A European Multicenter Observational Study. [PDF]
Objective Mepolizumab proved to be an efficacious treatment for eosinophilic granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the randomized, controlled MIRRA trial. In a few recently reported studies, successful real‐life experiences with the approved dose for treating severe eosinophilic asthma (100 mg every 4 weeks) were ...
Bettiol A +55 more
europepmc +2 more sources
Overlapping forms of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis: Insights from a European multicenter study. [PDF]
Abstract Background Granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) are distinct forms of antineutrophil cytoplasm antibody (ANCA)‐associated vasculitis (AAV). Increasing evidence suggests overlapping features, particularly in proteinase 3 (PR3)‐ANCA‐positive EGPA and GPA with eosinophilia.
Pallotti F +45 more
europepmc +2 more sources
Our study shows the importance of growth conditions when evaluating the seed size versus number trade‐off. Stressful conditions, such as warmer temperatures, can restrain the ability of plants to reach optimal investment in reproduction, masking the trade‐off.
Rocco F. Notarnicola +3 more
wiley +1 more source
A visual testament by Luca Riva, a deaf and mute pupil of the Procaccini
Abstract The paper investigates the visual testament by Luca Riva, a mute and deaf artist who studied in Milan under Camillo Procaccini. Dated 9 September 1624, the document consists of twelve folios bound together in a small volume. On the sheets, ten brown‐ink drawings illustrate the beneficiaries of Riva’s testament, identifying the inheritance ...
Angelo Lo Conte
wiley +1 more source
Women on top: Coital positions and gender hierarchies in Renaissance Italy
Abstract According to Christian theology, the ‘missionary’ position was the only proper way to have sex. Among clerical as well as secular authors, one of the most serious deviations from this prescription was the position with the woman on top of the man.
Marlisa Den Hartog
wiley +1 more source
Synergies of planning for forests and planning for Natura 2000: Evidences and prospects from northern Italy [PDF]
Improvements in the management of Natura 2000 sites are essential to achieve the targets set out by the Habitats and Birds Directives of the European Union.
Campagnaro, Thomas +3 more
core +1 more source
Disturbances, robustness and adaptation in forest commons: comparative insights from two cases in the Southeastern Alps [PDF]
Exposure to disturbances of different nature and scale can represent a threat for the survival of rural communities but also a stimulus to adjustment.
Gatto, Paola, Nevenka, Bogataj
core +1 more source
Oggetti diretti e indiretti in Italiano
Nella classificazione degli elementi costitutivi della frase le grammatiche italiane, trattando degli oggetti, si limitano di regola agli oggetti diretti, dipendenti cioè da verbi transitivi. Gli oggetti indiretti, ossia preposizionali, vengono relegati
Josip Jemej
doaj +1 more source
Duchowość monastyczna św. Ambrożego
L'apporto principale di sant'Ambrogio al tema consiste nell'aver inaugurato nel mondo latino la connessione della verginita eon la vita comunitaria, anziche concepirla come scelta individuale, cosicche lo scritto assume i caratteri di regola di vita ...
Bazyli Degórski
doaj +1 more source
La legge di Grassmann in greco come regola morfologica
Grassmann’s Law in Greek as morphological rule. Grassmann’s Law ‒ the phonetic change by virtue of which in an original diaspirate root a (regressive) dissimilation process takes place ‒ is generally regarded as working in reduplicated verbal forms, see ...
Alessandro De Angelis
doaj +1 more source

