Results 101 to 110 of about 3,588,558 (310)
Robust continuum regression. [PDF]
Several applications of continuum regression (CR) to non-contaminated data have shown that a significant improvement in predictive power can be obtained compared to the three standard techniques which it encompasses (ordinary least squares (OLS ...
Croux, Christophe +3 more
core +3 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Oat holds significant importance in global agriculture and nutrition due to their adaptability and versatility. In the present study, Principal Component Analysis (PCA) and Regression analysis were carried out to identify the cause and effect ...
Rukoo Chawla1&2, Minakshi Jattan1, D.S. Phogat3, Babita Rani4, Deepankar Verma5, Naresh*1 and Prachi Mahla2
doaj +1 more source
IMPLICATIONS OF FISCAL STIMULI IN MACROECONOMIC PLANE AT THE LEVEL OF SOME DEVELOPED AND EMERGING COUNTRIES [PDF]
Determining an optimal tax system is one of the main goals of fiscal policy applied in countries looking for sustainable economic development. Acknowledging that tax deductions affect a country's entire economic activity, in the research carried out ...
VODĂ ALINA DANIELA, DOBROTĂ GABRIELA
doaj
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Semiparametric Regression Analysis under Imputation for Missing Response Data [PDF]
We develop inference tools in a semiparametric regression model with missing response data. A semiparametric regression imputation estimator, a marginal average estimator and a (marginal) propensity score weighted estimator are defined.
Qihua Wang +2 more
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Local linear regression for functional predictor and scalar response [PDF]
The aim of this work is to introduce a new nonparametric regression technique in the context of functional covariate and scalar response. We propose a local linear regression estimator and study its asymptotic behaviour.
Grané, Aurea +2 more
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

