Results 141 to 150 of about 26,999,079 (309)

High-precision integrated diffractive optical networks enabling regression analysis. [PDF]

Nat Commun
Chen C, Ding H, Yu Y, Zhang X.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Machine learning-based regression analysis of cyclopentane and cyclohexane molecular graphs. [PDF]

Sci Rep
Irfan M, Bashir N, Shahzad MU, Othman KM, Noorwalli A, Gaid ASA, Zafar EYO.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Semiparametric Regression Analysis under Imputation for Missing Response Data [PDF]

We develop inference tools in a semiparametric regression model with missing response data. A semiparametric regression imputation estimator, a marginal average estimator and a (marginal) propensity score weighted estimator are defined.
Qihua Wang, Wolfgang Haerdle, Oliver Linton   +2 more
core  

What Shapes Clinical Competence in Intensive Care Nurses? A Hierarchical Regression Analysis. [PDF]

Nurs Crit Care
Kurt H, Ceyhan Ö.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Functional form issues in the regression analysis of financial leverage ratios [PDF]

Linear models are typically used in the regression analysis of capital structure choices. However, given the proportional and bounded nature of leverage ratios, models such as the tobit, the fractional regression model and its two-part variant are a ...
Joaquim Ramalho, Jacinto Vidigal da Silva   +1 more
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Intra-Industry Spillovers from Inward FDI: A Meta-Regression Analysis [PDF]

The present paper conducts a meta-analysis of literature on intra-industry spillovers from foreign direct investment, using 97 different outcomes from 67 empirical studies. Apart from the traditional approach, robust meta-regression, random-effects model,
Zuzana Iršová, Tomáš Havránek
core