Results 31 to 40 of about 2,496,534 (248)

Genomic regression analysis of coordinated expression

open access: yesNature Communications, 2017
Somatic copy number alterations (SCNA) can confound gene co-expression analysis in cancers. Here the authors develop a method to remove the effects of SCNA in co-expression analysis, improving the analysis of network rewiring in cancer, and provide a ...
Ling Cai   +6 more
doaj   +1 more source

Stepwise cox regression analysis in SPSS

open access: yesCancer Research, Statistics, and Treatment, 2018
This article is a beginners' guide for performing Cox regression analysis in SPSS. The article provides practical steps toward performing Cox analysis and interpreting the output of SPSS for Cox regression analysis.
Sampada Dessai, Vijai Simha, Vijay Patil
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Consumer involvement in the product with general causality orientations [PDF]

open access: yesMarketing (Beograd. 1991), 2012
The main objective of the research relates to establish predictable values of causality orientation for types of consumer involvement in product. Beside that, the possible differences in expression of causality orientations and dimension of involvement ...
Matanović Jelena   +4 more
doaj   +1 more source

Regression trees to identify combinations of farming practices that achieve the best overall intrinsic quality of milk

open access: yesJournal of Dairy Science, 2023
: Many studies over the last 30 years have shown the effects of farming practices on milk compounds. Combinations of practices may have antagonistic or synergistic effects on milk compounds, but these combination effects remain underinvestigated ...
L. Rey-Cadilhac   +4 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Preponderantly increasing/decreasing data in regression analysis

open access: yesCroatian Operational Research Review, 2016
For the given data (wI, xI, yI ), i = 1, . . . , n, and the given model function f (x; θ), where θ is a vector of unknown parameters, the goal of regression analysis is to obtain estimator θ∗ of the unknown parameters θ such that the vector of residuals ...
Darija Marković
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

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