Results 31 to 40 of about 5,681,325 (336)

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Approximation Analysis of Learning Algorithms for Support Vector Regression and Quantile Regression

open access: yesJournal of Applied Mathematics, 2012
We study learning algorithms generated by regularization schemes in reproducing kernel Hilbert spaces associated with an ϵ-insensitive pinball loss. This loss function is motivated by the ϵ-insensitive loss for support vector regression and the pinball ...
Dao-Hong Xiang, Ting Hu, Ding-Xuan Zhou
doaj   +1 more source

Fuzzy Regression Analysis with an Application [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2006
This work investigates the analysis of fuzzy regression in case of the data being fuzzy or non-fuzzy. The analysis is performed by several methods , such as fuzzy linear regression (FLR) and modified one, and fuzzy linear regression with least squares (
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Multiple Regression Analysis: SFA Professors\u27 Salaries [PDF]

open access: yes, 2010
There is always a certain curiosity and controversy surrounding professor’s salaries and whether they are overpaid or not paid enough. We have decided to try and untangle this wonder by creating a regression model in which the average person could easily
Edmeade, LaTonya
core   +1 more source

Practical Comparison of Results of Statistic Regression Analysis and Neural Network Regression Analysis

open access: yesLittera Scripta, 2016
There are many discussions and arguments about accuracy of the results of statistic regression analysis and neural network regression analysis among experts. Of course all of them look for the best method usable in practice.
Marek Vochozka
doaj  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Genomic regression analysis of coordinated expression

open access: yesNature Communications, 2017
Somatic copy number alterations (SCNA) can confound gene co-expression analysis in cancers. Here the authors develop a method to remove the effects of SCNA in co-expression analysis, improving the analysis of network rewiring in cancer, and provide a ...
Ling Cai   +6 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy