Results 71 to 80 of about 2,557,184 (280)
Brazilian Journal of Poultry ScienceIn this study, the influence of carcass parts weights (thigh, breast, wing, back weight, gizzard, heart, and feet) on whole carcass weight of white turkeys (Big-6) was analyzed by regression analysis based on ridge regression and factor analysis scores ...
Ş Çelik +6 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Electronic Journal of Plant BreedingOat holds significant importance in global agriculture and nutrition due to their adaptability and versatility. In the present study, Principal Component Analysis (PCA) and Regression analysis were carried out to identify the cause and effect ...
Rukoo Chawla1&2, Minakshi Jattan1, D.S. Phogat3, Babita Rani4, Deepankar Verma5, Naresh*1 and Prachi Mahla2
doaj +1 more source
IMPLICATIONS OF FISCAL STIMULI IN MACROECONOMIC PLANE AT THE LEVEL OF SOME DEVELOPED AND EMERGING COUNTRIES [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2018 Determining an optimal tax system is one of the main goals of fiscal policy applied in countries looking for sustainable economic development. Acknowledging that tax deductions affect a country's entire economic activity, in the research carried out ...
VODĂ ALINA DANIELA, DOBROTĂ GABRIELA
doaj
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis [PDF]
, 2018 R. Meister +7 more
openalex +1 more source