Results 71 to 80 of about 5,681,325 (336)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Regression modeling of different proteins using linear and multiple analysis [PDF]

open access: yesNetwork Biology, 2017
There are different types of regression analysis. Out of which simple regression and multiple regressions was considered in this paper. For calculation purpose we have used PLS analysis which calculates squared r values.
Shruti Jain
doaj  

Children's understanding of financial literacy and parents' choice of financial knowledge learning methods in Malaysia

open access: yesMethodsX, 2023
Financial literacy is an essential lifelong skill that should be taught to children at any age. It holds the key to develop a generation of adults who are knowledgeable about money and the economy.
Logasvathi Murugiah   +4 more
doaj  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Image metadata estimation using independent component analysis and regression [PDF]

open access: yes, 2006
In this paper, we describe an approach to camera metadata estimation using regression based on Independent Component Analysis (ICA). Semantic scene classification of images using camera metadata related to capture conditions has had some success in the ...
Blighe, Michael   +2 more
core  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

MODELING ROMANIANS’ LEVEL OF LIFE SATISFACTION [PDF]

open access: yesRevista Română de Statistică, 2012
As a multi-dimensional indicator that captures the quality of life and wellbeing, the level of life satisfaction is very important for designing future policy The present analysis will focus on the study of life satisfaction based on the Romanian ...
Roxana-Otilia-Sonia HRIŢCU
doaj  

A Speed Regression Using Acceleration Data in a Deep Convolutional Neural Network

open access: yesIEEE Access, 2019
A speed estimation method using the acceleration data measured by a wearable device during exercising on a treadmill is described in this paper. The moving speed is estimated by a regression algorithm that implements a deep convolutional neural network ...
Karl L. Wang, Jingya Xu
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Illusions in regression analysis

open access: yesInternational Journal of Forecasting, 2011
Soyer and Hogarth’s article, 'The Illusion of Predictability,' shows that diagnostic statistics that are commonly provided with regression analysis lead to confusion, reduced accuracy, and overconfidence. Even highly competent researchers are subject to these problems.
openaire   +5 more sources

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