Results 61 to 70 of about 7,030,691 (326)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Effectiveness of selection response on F3 and F4 generations for grain yield and yield attributing traits in aromatic rice (Oryza sativa L.)

open access: yesElectronic Journal of Plant Breeding, 2018
Genetic variability present in the F2 generation originating from ten crosses of rice genotypes, selection was practiced for high grain yield. Expected selection response was estimated in F3 generations and compared with F2 generation.
N.R. Koli and, B.K. Patidar
doaj   +1 more source

Modeling of a solar air collector heat transfer coefficient with regression algorithms

open access: yesFirat University Journal of Experimental and Computational Engineering, 2022
Solar air collectors (SAC) are thermodynamic systems that convert solar energy into useful fluid energy. SACs are very common in heating, cooling, food drying, and many other low-temperature applications.
Mehmet Daş, Ebru Kavak Akpınar
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Standardised regression coefficient as an effect size index in summarising findings in epidemiological studies

open access: yesEpidemiology Biostatistics and Public Health, 2013
Background: a major problem in evaluating and reviewing the published findings of studies on the association between a quantitative explanatory variable and a quantitative dependent variable is that the results are analysed and reported in many ...
P. Nieminen   +4 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Convex Optimization Methods for Dimension Reduction and Coefficient Estimation in Multivariate Linear Regression [PDF]

open access: yes, 2008
In this paper, we study convex optimization methods for computing the trace norm regularized least squares estimate in multivariate linear regression. The so-called factor estimation and selection (FES) method, recently proposed by Yuan et al.
Lu, Zhaosong   +2 more
core   +3 more sources

Estimating spatial quantile regression with functional coefficients: A robust semiparametric framework

open access: yes, 2014
This paper considers an estimation of semiparametric functional (varying)-coefficient quantile regression with spatial data. A general robust framework is developed that treats quantile regression for spatial data in a natural semiparametric way.
Cheng, Longsheng   +2 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

A new time-varying coefficient regression approach for analyzing infectious disease data

open access: yesScientific Reports, 2023
Since the beginning of the global pandemic of Coronavirus (SARS-COV-2), there has been many studies devoted to predicting the COVID-19 related deaths/hospitalizations. The aim of our work is to (1) explore the lagged dependence between the time series of
Juxin Liu   +6 more
doaj   +1 more source

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