Results 121 to 130 of about 492,713 (327)

Education Production Function and Class-Size Effects in Japanese Public Schools [PDF]

Education production functions are estimated using student-level achievement data for Japanese students, with emphasis on estimating the causal effect of class size on students' academic performance.
Masakazu Hojo
core  

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Regression Discontinuity Designs in Economics

, 2009
This paper provides an introduction and "user guide" to Regression Discontinuity (RD) designs for empirical researchers. It presents the basic theory behind the research design, details when RD is likely to be valid or invalid given economic incentives, explains why it is considered a "quasi-experimental" design, and summarizes different ways (with ...
Lee, David S., Lemieux, Thomas
openaire   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Using Regression Discontinuity Design to Identify the Effect of Zoning [PDF]

We test the effect of minimum lot zoning on rural-to-urban land use conversion using Regression Discontinuity Design (RDD), a technique that exploits natural discontinuities in the data to identify causal effects.
Carrion-Flores, Carmen E., Irwin, Elena G.   +1 more
core   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Political Dynasties and Local Spending in Indonesia

Jurnal Ekonomi Pembangunan
Does political dynasty affect local spending in Indonesia?  Only a few articles have taken up the political economy issues in Indonesia This study provides empirical analysis that focuses on explaining the effect of the political competition through ...
Dwi Putri Larasati, Jahen Fachrul Rezki
doaj   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

The impact of deep brain stimulation payment adjustments on healthcare utilization in Shanghai, China: a regression discontinuity analysis of health insurance claims

BMC Health Services Research
Background and objectives Recently, the financial burden on medical insurance funds has increased rapidly. The policy effects of paying for innovation await scientific measurement.
Qian Xing, Tianchi Chen, Hongfei Hu, Da He, Wei Wang, Yue Yin, Haiyin Wang   +6 more
doaj   +1 more source

The impact of local taxes on plants location decision [PDF]

Determinants of plant locations are known to be multiple. Locations of partners and competitors are crucial, as well as the territory's local characteristics. Some local characteristics can be natural.
P. SILLARD, R. RATHELOT
core