Results 101 to 110 of about 353,670 (291)

Local Likelihood Estimation of Truncated Regression and Its Partial Derivatives: Theory and Application [PDF]

In this paper we propose a very flexible estimator in the context of truncated regression that does not require parametric assumptions. To do this, we adapt the theory of local maximum likelihood estimation.
Byeong U. Park, Leopold Simar, Valentin Zelenyuk   +2 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Ridge regression revisited [PDF]

We argue in this paper that general ridge (GR) regression implies no major complication compared with simple ridge regression. We introduce a generalization of an explicit GR estimator derived by Hemmerle and by Teekens and de Boer and show that this ...
Boer, P.M.C. de, Hafner, C.M.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A Refined Regression Estimator for General Inverse Adaptive Cluster Sampling

Mathematics
Adaptive cluster sampling (ACS) is a sampling technique commonly used for rare populations that exhibit spatial clustering. However, the initially selected sample units may not always satisfy the specified inclusion condition.
Nipaporn Chutiman, Supawadee Wichitchan, Chawalit Boonpok, Monchaya Chiangpradit, Pannarat Guayjarernpanishk   +4 more
doaj   +1 more source

PERBANDINGAN REGRESI ROBUST PENDUGA MM DENGAN METODE RANDOM SAMPLE CONSENSUS DALAM MENANGANI PENCILAN

E-Jurnal Matematika, 2014
The presence of outliers in observation can result in biased in parameter estimation using ordinary least square (OLS). Robust regression MM-estimator is one of the estimations methods that able to obtain a robust estimator against outliers.
NI PUTU NIA IRFAGUTAMI, I GUSTI AYU MADE SRINADI, I WAYAN SUMARJAYA   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

An analysis of the indicator saturation estimator as a robust regression estimator.. [PDF]

An algorithm suggested by Hendry (1999) for estimation in a regression with more regressors than observations, is analyzed with the purpose of finding an estimator that is robust to outliers and structural breaks.
Johansen, Søren, Nielsen, Bent
core   +1 more source

Bootrapping robust estimates of regression

The Annals of Statistics, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Salibian-Barrera, Matias, Zamar, Ruben H.   +1 more
openaire   +3 more sources