Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
A Logistic Regression Model Integrating Flow Cytometry-Derived Immune Cell Profiles and Hematological Parameters for Preoperative Prediction of Peritoneal Metastasis in Gastric Cancer. [PDF]
Cancers (Basel)Zhao R, Ju Y, Yu Z, Xue Y, Song H.
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Predicting ICU Delirium with a Regularized Logistic Regression Model: Device-Support Burden as an Informative Predictor Domain in a Turkish Cohort. [PDF]
Diagnostics (Basel)Bazna MS, Okumuş F.
europepmc +1 more source
Aging and Cancer, EarlyView.In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
A Stacking-Enhanced Support Vector Regression Model for Predicting the Hot Deformation Flow Stress of TC18 Alloy. [PDF]
Materials (Basel)Jiang X +5 more
europepmc +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Developing machine learning regression model optimized using Tabu search harmony search algorithm for prediction of mass transfer in membranes. [PDF]
Sci RepAbu-Hamdeh NH, Milyani AH, Almitani KH.
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Infrared Thermographic Evaluation of Exothermic Temperature Changes During the Setting Reaction of Six Dental Impression Gypsums: An In Vitro Linear Regression Model. [PDF]
Dent J (Basel)Mauricio F +6 more
europepmc +1 more source