Results 81 to 90 of about 7,473,929 (357)

Regular expression based pattern extraction from a cell - Specific gene expression data

Informatics in Medicine Unlocked, 2019
Cancer cells are formed when active genes stop functioning properly. Timely activation of a gene is governed through the combined effort of multiple Transcription Factors (TFs). TFs are proteins that bind on DNA in a sequence-specific manner.
Suja Subramanian, Tessamma Thomas
doaj   +1 more source

The regular part of second-order differential sectorial forms with lower-order terms

, 2013
We present a formula for the regular part of a sectorial form that represents a general linear second-order differential expression that may include lower-order terms. The formula is given in terms of the original coefficients.
Sauter, Manfred, ter Elst, A. F. M.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Boundedness in languages of infinite words

, 2017
We define a new class of languages of $\omega$-words, strictly extending $\omega$-regular languages. One way to present this new class is by a type of regular expressions.
Bojańczyk, Mikołaj, Colcombet, Thomas
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Tumor necrosis factor gene expression in regular hemodialysis patients

Saudi Journal of Kidney Diseases and Transplantation, 2015
This study evaluates tumor necrosis factor (TNF)-alfa gene expression in patients with end-stage renal disease (ESRD) on regular hemodialysis as an expression of cardiovascular disease (CVD) risk even on a sub-clinical level and its relation to some of ...
Hemmat E El Haddad, Mohamed A Marie, Tarek M Samy, Reem Jan Farid, Mai Sherif, Usama A Sharaf El Din   +5 more
doaj   +1 more source

State Elimination Ordering Strategies: Some Experimental Results

, 2010
Recently, the problem of obtaining a short regular expression equivalent to a given finite automaton has been intensively investigated. Algorithms for converting finite automata to regular expressions have an exponential blow-up in the worst-case.
Davide Nabais, Giovanni Pighizzini, Ian McQuillan, Nelma Moreira, Rogério Reis   +4 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Deafness mutation mining using regular expression based pattern matching

BMC Medical Informatics and Decision Making, 2007
Background While keyword based queries of databases such as Pubmed are frequently of great utility, the ability to use regular expressions in place of a keyword can often improve the results output by such databases. Regular expressions can allow for the
Frenz Christopher M
doaj   +1 more source