Results 71 to 80 of about 752,176 (316)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A novel algorithm for the conversion of shuffle regular expressions into non-deterministic finite automata [PDF]

open access: yesMaejo International Journal of Science and Technology, 2013
Regular expressions with shuffle operators are widely used in diverse fields of computer science. The work presented here investigates the shuffling of regular expressions and their conversion into non-deterministic finite automata.
Ajay Kumar, Anil Kumar Verma
doaj   +1 more source

Short-term regular moderate exercise improved male hypothalamic-pituitary-gonadal axis function via the reduction of hypothalamic neurokinin B expression in adult rats [PDF]

open access: diamond, 2021
Nazli Khajehnasiri   +5 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Regular Expressions for Humanists [PDF]

open access: yes, 2017
A getting started guide on regular expressions for humanities ...
Eve, Martin Paul
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Novel NFA engine construction method of regular expressions

open access: yesTongxin xuebao, 2014
A novel method for constructing smaller non-deterministic finite automata (NFA) engine from given regular expressions named PFA was proposed.There are three main algorithms in PFA,the pretreatment algorithm,the coding parser tree algorithm and the NFA ...
Mao-hua JING   +3 more
doaj   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

FungiRegEx: A Tool for Pattern Identification in Fungal Proteomic Sequences Using Regular Expressions

open access: yesApplied Sciences
In the context of proteomic-scale research, it is imperative to automatically analyze numerous species and subspecies to discern distinctive characteristics present in multiple species of the fungi kingdom that contain sequences of interest that could ...
Victor Terrón-Macias   +4 more
doaj   +1 more source

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