Results 91 to 100 of about 587,527 (280)

Generation of strongly regular graphs from quaternary complex Hadamard matrices

open access: yesCeylon Journal of Science, 2018
A strongly regular graph with parameters (v, k, μ, λ) is a regular graph G with v vertices and k degree in which every two adjacent vertices have λ common neighbors and every two non-adjacent vertices have μ common neighbors. In this paper, we propose an
W. V. Nishadi   +3 more
doaj   +1 more source

The k-conversion number of regular graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2020
Given a graph and a set an irreversible k -threshold conversion process on G is an iterative process wherein, for each St is obtained from by adjoining all vertices that have at least k neighbors in We call the set S0 the seed set of the process, and ...
Christina M. Mynhardt, Jane L. Wodlinger
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Directed strongly walk-regular graphs

open access: yes, 2017
We generalize the concept of strong walk-regularity to directed graphs. We call a digraph strongly $\ell$-walk-regular with $\ell >1$ if the number of walks of length $\ell$ from a vertex to another vertex depends only on whether the two vertices are the
Omidi, Gholamreza, van Dam, Edwin R.
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Handicap Labelings of 4-Regular Graphs

open access: yesAdvances in Electrical and Electronic Engineering, 2017
Let G be a simple graph, let f : V(G)→{1,2,...,|V(G)|} be a bijective mapping. The weight of v ∈ V(G) is the sum of labels of all vertices adjacent to v. We say that f is a distance magic labeling of G if the weight of every vertex is the same
Petr Kovar   +3 more
doaj   +1 more source

Regular Kn-free graphs

open access: yesJournal of Combinatorial Theory, Series B, 1983
AbstractTriples (p, n, r) for which there exists an r-regular Kn-free graph on p points are determined.
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Domination in 4-regular Knödel graphs

open access: yesOpen Mathematics, 2018
A subset D of vertices of a graph G is a dominating set if for each u ∈ V(G) ∖ D, u is adjacent to some vertex v ∈ D. The domination number, γ(G) of G, is the minimum cardinality of a dominating set of G.
Mojdeh Doost Ali, Musawi S.R., Nazari E.
doaj   +1 more source

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