Results 101 to 110 of about 587,527 (280)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The reflexive edge strength on some almost regular graphs. [PDF]
Heliyon, 2021 Agustin IH +4 more
europepmc +1 more source
It Is Better to Be Semi-Regular When You Have a Low Degree
EntropyWe study the algebraic connectivity for several classes of random semi-regular graphs. For large random semi-regular bipartite graphs, we explicitly compute both their algebraic connectivity as well as the full spectrum distribution. For an integer d∈3,7,
Theodore Kolokolnikov
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Spectral analysis of transient amplifiers for death-birth updating constructed from regular graphs. [PDF]
J Math Biol, 2021 Richter H.
europepmc +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Regular subgraphs of linear extension graphs [PDF]
Математичні Студії, 2011 The paper deals with the properties of regular subgraphs of linear extension graphs. We obtain a necessary and sufficient condition for regularity of linear extension graphs, prove a pro- position on cardinality and degree partition of special linear ...
O. S. Bondarenko
doaj
Regular packings of regular graphs
Discrete Mathematics, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gutiérrez, A., Lladó, A.S.
openaire +2 more sources
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Regular graphs with regular neighborhoods [PDF]
Glasgow Mathematical Journal, 1992 The existence of r-regular graphs such that each edge lies in exactly t triangles, for given integers t < r, is studied. If t is sufficiently close to r then each such connected graph has to be the complete multipartite graph. Relations to graphs with isomorphic neighborhoods are also considered.
openaire +2 more sources