Results 81 to 90 of about 587,527 (280)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Remarks on the energy of regular graphs

open access: yes, 2016
The energy of a graph is the sum of the absolute values of the eigenvalues of its adjacency matrix. This note is about the energy of regular graphs. It is shown that graphs that are close to regular can be made regular with a negligible change of the ...
Nikiforov, V.
core   +1 more source

Construction of Cospectral Integral Regular Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2017
Graphs G and H are called cospectral if they have the same characteristic polynomial. If eigenvalues are integral, then corresponding graphs are called integral graph.
Bapat Ravindra B., Karimi Masoud
doaj   +1 more source

Approximately strongly regular graphs

open access: yesDiscrete Mathematics, 2023
We give variants of the Krein bound and the absolute bound for graphs with a spectrum similar to that of a strongly regular graph. In particular, we investigate what we call approximately strongly regular graphs. We apply our results to extremal problems. Among other things, we show the following: (1) Caps in $\mathrm{PG}(n, q)$ for which the number of
openaire   +3 more sources

On $k$-Walk-Regular Graphs [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2009
Considering a connected graph $G$ with diameter $D$, we say that it is $k$-walk-regular, for a given integer $k$ $(0\leq k \leq D)$, if the number of walks of length $\ell$ between any pair of vertices only depends on the distance between them, provided that this distance does not exceed $k$. Thus, for $k=0$, this definition coincides with that of walk-
Dalfó Simó, Cristina   +2 more
openaire   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Graphs with Clusters Perturbed by Regular Graphs—Aα-Spectrum and Applications

open access: yesDiscussiones Mathematicae Graph Theory, 2020
Given a graph G, its adjacency matrix A(G) and its diagonal matrix of vertex degrees D(G), consider the matrix Aα (G) = αD(G) + (1 − α)A(G), where α ∈ [0, 1).
Cardoso Domingos M.   +2 more
doaj   +1 more source

Distance-Regular Graphs and Halved Graphs

open access: yesEuropean Journal of Combinatorics, 1986
Let G be a bipartite distance-regular graph with bipartition \(V(G)=X\cup Y\). Let \(V(G')=X\) and, for x and y in X, let x be adjacent to y in G' if and only if x is of distance two from y in G. Then G' is called a halved graph of G, and is distance-regular. This paper discusses whether G' is one of the known, large-diameter, distance-regular graphs.
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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