Results 81 to 90 of about 1,782,235 (292)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The limited regular languages

open access: yesTheoretical Computer Science, 1988
AbstractThis paper is a continuation of [3]. It gives some further properties of limited regular languages and partial solutions to two of S. Eilenberg's open problems [2, p. 158].
Chang-jie Tang, Yili Zhang
openaire   +2 more sources

Caterpillar Dualities and Regular Languages [PDF]

open access: yesSIAM Journal on Discrete Mathematics, 2013
We characterize obstruction sets in caterpillar dualities in terms of regular languages, and give a construction of the dual of a regular family of caterpillars. We show that these duals correspond to the constraint satisfaction problems definable by a monadic linear Datalog program with at most one EDB per rule.
Péter L. Erdös   +2 more
openaire   +3 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Regular language quantum states [PDF]

open access: yesQuantum
We introduce regular language states, a family of quantum many-body states. They are built from a special class of formal languages, called regular, which has been thoroughly studied in the field of computer science.
Marta Florido-Llinàs   +3 more
doaj   +1 more source

Maximally Atomic Languages [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
The atoms of a regular language are non-empty intersections of complemented and uncomplemented quotients of the language. Tight upper bounds on the number of atoms of a language and on the quotient complexities of atoms are known.
Janusz Brzozowski, Gareth Davies
doaj   +1 more source

Parameterized regular expressions and their languages

open access: yesTheoretical Computer Science, 2013
We study regular expressions that use variables, or parameters, which are interpreted as alphabet letters. We consider two classes of languages denoted by such expressions: under the possibility semantics, a word belongs to the language if it is denoted by some regular expression obtained by replacing variables with letters; under the certainly ...
Pablo Barceló   +2 more
openaire   +10 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Regular expression matching with input compression and next state prediction. [PDF]

open access: yes, 2008
Automata based regular expression matching can often require large amounts of memory for its state transition tables, particularly when matching multiple complex regular expressions with the same automata.
Tripp, Gerald
core  

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