Results 111 to 120 of about 4,315 (225)

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Browsing FAIR Transformation Product Information with FAIR-TPs. [PDF]

ACS Environ Au
Mayahi B, Palm EH, Schymanski EL.
europepmc   +1 more source

Chemically Programmable Underwater Sound‐Absorbing Metamaterial via MXene Self‐Assembly

Advanced Science, EarlyView.
MXene self‐assembly creates a chemically programmable underwater metamaterial with quasi‐periodic layers and a chemical‐physical multi‐level constraint system. A crosslinker as a ‘chemical scissor’ precisely edits microscopic interactions, exciting deep‐subwavelength strong local resonances that induce near‐zero/negative effective bulk modulus (Keff ...
Ziwen Gan, Ranran Qi, Mingyi Liao, Bowen Chen, Chen Cheng, Wei Tu   +5 more
wiley   +1 more source

Brain‐Computer Interface Training Fosters Perceptual Skills to Detect Errors

Advanced Science, EarlyView.
Accurate perception of visuomotor errors underpins motor precision and learning, yet conventional behavioral training fails to improve sensitivity to subtle errors. Real‐time EEG‐based brain‐computer interface feedback targeting the error positivity component enhances perceptual learning of small errors.
Deland H. Liu, Fumiaki Iwane, Minsu Zhang, Leonardo G. Cohen, José del R. Millán   +4 more
wiley   +1 more source

RTS-Net: thyroid nodule segmentation network integrating dual-path attention and graph convolution. [PDF]

Front Med (Lausanne)
Sun X, Li X, Yang Z, Zhang B, Liu Y, Liang H, Guo W, Liang Y, Chen X, Li X, Wang B, Wang X.   +11 more
europepmc   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Beyond <i>Omakase</i>: Designing Shared Control for Navigation Robots with Blind People. [PDF]

Proc SIGCHI Conf Hum Factor Comput Syst
Kamikubo R, Kayukawa S, Kaniwa Y, Wang A, Kacorri H, Takagi H, Asakawa C.   +6 more
europepmc   +1 more source

Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics

Advanced Science, EarlyView.
Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai, Ri He, Junxian Liu, Liangzhi Kou   +3 more
wiley   +1 more source

A Suite of LMs Comprehend Puzzle Statements as Well or Better Than Humans. [PDF]

Open Mind (Camb)
Rakshit S, Hu J, Mahowald K, Goldberg AE.   +3 more
europepmc   +1 more source