FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Cross-time analysis of physical exercise and traditional gender concepts: Chinese women in the CGSS 2013 and 2023. [PDF]
BMC Public HealthSun L, Fang P.
europepmc +1 more source
Bridging the gap between a stationary point process and its palm distribution
Stationary Point;probability ...
Nieuwenhuis, G.
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Oncology Organization and Oncologist Networks Under Medicare Advantage Plans.
JAMA Netw OpenHu X +10 more
europepmc +1 more source
Third molars surgical extraction awareness: a cross-sectional questionnaire-based survey. [PDF]
Oral Maxillofac SurgBorovec J +5 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Epithelial thickness gradients as a diagnostic biomarker for early-stage keratoconus. [PDF]
Int OphthalmolJansone-Langina Z +4 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Healthcare Access and Diagnostic Imaging Care Pathways for Musculoskeletal Conditions in Canada: A Cross-Sectional Analysis of the Canadian Community Health Survey 2022. [PDF]
CureusMamah CJ +6 more
europepmc +1 more source