Results 31 to 40 of about 653,519 (263)

Affine processes are regular

, 2009
We show that stochastically continuous, time-homogeneous affine processes on the canonical state space $\Rplus^m \times \RR^n$ are always regular. In the paper of \citet{Duffie2003} regularity was used as a crucial basic assumption.
Keller-Ressel, Martin, Schachermayer, Walter, Teichmann, Josef   +2 more
core   +4 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Characterizations of Super-regularity and its Variants

, 2018
Convergence of projection-based methods for nonconvex set feasibility problems has been established for sets with ever weaker regularity assumptions.
A Daniilidis, AS Lewis, D Aussel, DR Luke, HH Bauschke, HH Bauschke, HV Ngai, J Bolte, MN Dao, R Hesse, RA Poliquin   +10 more
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

On the continuity of solutions to advection-diffusion equations with slightly super-critical divergence-free drifts

Advances in Nonlinear Analysis, 2014
We address the regularity of solutions to elliptic and parabolic equations of the form -Δu+b·∇u=0${- \Delta u+b\cdot \nabla u=0}$ and ut-Δu+b·∇u=0${u_t- \Delta u+b\cdot \nabla u=0}$ with divergence-free drifts b.
Ignatova Mihaela
doaj   +1 more source

الالتزام بالمذاهب الأربعة بين الانضباط والجمود - تحليل ومقارنة

Marifetname, 2022
من المعلوم في أصول الفقه أنَّ المكلَّف إما أن يكون مجتهداً أو مقلِّداً، فالأول هو القادر على استنباط الأحكام الشرعية من أدلتها مباشرةً، وهذا واجبهُ الاجتهاد، والثاني هوالعاجز عن استنباط الأحكام من أدلتها، وهذا عليه أن يقلِّد اﻟﻤﺠتهدين، وقد شاع بين ...
Mohammad Rachıd Aldershawi
doaj   +1 more source

Non-Autonomous Maximal Regularity in Hilbert Spaces

, 2016
We consider non-autonomous evolutionary problems of the form $u'(t)+A(t)u(t)=f(t)$, $u(0)=u_0,$ on $L^2([0,T];H)$, where $H$ is a Hilbert space.
Dier, Dominik, Zacher, Rico
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Linear syzygies, flag complexes, and regularity

, 2014
We show that for every positive integer R there exist monomial ideals generated in degree two, with linear syzygies, and regularity of the quotient equal to R. Such examples can not be found among Gorenstein ideals since the regularity of their quotients
Constantinescu, Alexandru, Kahle, Thomas, Varbaro, Matteo   +2 more
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source