Results 61 to 70 of about 161,720 (314)

Theoretical observers for infinite dimensional skew-symmetric systems

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020
The observer construction has a main importance in the control theory and its applications for the systems of infinite dimension. Even if the system’ state has an infinite dimension, its estimation is given using some physical measures of finite ...
Judicael Deguenon, Barbulescu Alina
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Regularity of weak solutions to the 3D stationary tropical climate model

Open Mathematics
This article studies the regularity of weak solutions to the 3D stationary tropical climate model. We prove that when (U,V,θ)\left(U,V,\theta ) belongs to the homogeneous Morrey space M˙2,p(R3){\dot{M}}^{2,p}\left({{\mathbb{R}}}^{3}) with p>3p\gt 3, then
Song Huiyang, Bie Qunyi, Zhou Yanping
doaj   +1 more source

The Singular Perturbation Problem for a Class of Generalized Logistic Equations Under Non-classical Mixed Boundary Conditions

Advanced Nonlinear Studies, 2019
This paper studies a singular perturbation result for a class of generalized diffusive logistic equations, d⁢ℒ⁢u=u⁢h⁢(u,x){d\mathcal{L}u=uh(u,x)}, under non-classical mixed boundary conditions, ℬ⁢u=0{\mathcal{B}u=0} on ∂⁡Ω{\partial\Omega}.
Fernández-Rincón Sergio, López-Gómez Julián   +1 more
doaj   +1 more source

Regular Hypermaps

European Journal of Combinatorics, 1988
This paper studies the correspondence between topological hypermaps and algebraic hypermaps. A topological map is a decomposition of a surface into polygonal cells. A topological hypermap is a similar decomposition of an orientable surface with the ``edges'' and ``vertices'' (hyperedges and hypervertices) homeomorphic to closed discs.
David Corn, David Singerman
openaire   +2 more sources

To Regularize or Not To Regularize? The Bias Variance Trade-off in Regularized AEs

CoRR, 2020
Regularized Auto-Encoders (RAEs) form a rich class of neural generative models. They effectively model the joint-distribution between the data and the latent space using an Encoder-Decoder combination, with regularization imposed in terms of a prior over the latent space.
Arnab Kumar Mondal, Himanshu Asnani, Parag Singla, Prathosh AP   +3 more
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Regular factors in regular graphs

Discrete Mathematics, 1993
The author shows that a \(k\)-regular \((k-1)\)-edge-connected graph with an even number of vertices has an \(m\)-factor not containing \(k-m\) arbitrarily prescribed edges whenever \(1\leq m\leq k-1\). This was known only for \(m=1\) or \(k-1\). Also the sharpness of this result and some corollaries are given.
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Lorentz estimates for asymptotically regular elliptic equations in quasiconvex domains

Electronic Journal of Differential Equations, 2016
We derive a global Lorentz estimate of the gradient of weak solutions to nonlinear elliptic problems with asymptotically regular nonlinearity in quasiconvex domains.
Junjie Zhang, Shenzhou Zheng
doaj