Results 61 to 70 of about 88,370 (267)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Regularity of planar flows for shear-thickening fluids under perfect slip boundary conditions

open access: yesElectronic Journal of Differential Equations, 2014
For evolutionary planar flows of shear-thickening fluids in bounded domains we prove the existence of a solution with the Holder continuous velocity gradients and pressure. The problem is equipped with perfect slip boundary conditions.
Jakub Tichy
doaj  

Regular antilattices

open access: yesThe Art of Discrete and Applied Mathematics, 2019
Antilattices $(S;\lor, \land)$ for which the Green's equivalences $\mathcal L_{(\lor)}$, $\mathcal R_{(\lor)}$, $\mathcal L_{(\land)}$ and $\mathcal R_{(\land)}$ are all congruences of the entire antilattice are studied and enumerated.
Cvetko-Vah, Karin   +3 more
openaire   +4 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Judgement of paintings belonging to different tendencies in the 20th century painting [PDF]

open access: yesPsihologija, 2004
In this study Trifunović’ hypothesis that there are three objective lines in the development of modern art was psychologically evaluated. According to Trifunović, in the first line (Cézanne - cubism - neoplasticism - suprematism) the geometrization of ...
Radonjić Ana, Marković Slobodan
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Lithuanian on-line periodicals on the World Wide Web

open access: yesInformation Research: An International Electronic Journal, 2001
Deals with Lithuanian full-text electronic periodicals distributed through the World Wide Web. An electronic periodical is usually defined as a regular publication on some particular topic distributed in digital form, chiefly through the Web, but also by
Lina Sarlauskiene
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

ENTROPİ, ŞANS VE TANRI

open access: yesFelsefe Dünyası, 2014
Evrenin bir başlangıcının olup olmadığı ya da bu düzenin nereden geldiğigibi sorular, insanlığın en büyük merakıdır. Fakat 18. Yüzyılda sanayi devrimininürünü olan buhar makinelerinin çalışma prensiplerinin keşfiyle birlikte doğan termodinamikve ...
Fatih Özgökman
doaj  

Nonoccurrence of Lavrentiev gap for a class of functionals with nonstandard growth

open access: yesAdvances in Nonlinear Analysis
We consider the functional ℱ(u)≔∫Ωf(x,Du(x))dx,{\mathcal{ {\mathcal F} }}\left(u):= \mathop{\int }\limits_{\Omega }f\left(x,Du\left(x)){\rm{d}}x, where f(x,z)f\left(x,z) satisfies a (p,q)\left(p,q)-growth condition with respect to zz and can be ...
De Filippis Filomena   +2 more
doaj   +1 more source

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