Results 41 to 50 of about 100,154 (263)
Comparing parameter choice methods for regularization of ill-posed problems [PDF]
, 2011 In the literature on regularization, many different parameter choice methods have been proposed in both deterministic and stochastic settings. However, based on the available information, it is not always easy to know how well a particular method will ...
Bauer, F., Lukas, M.A.
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
AxiomsThis paper studies a particular type of planar Filippov system that consists of two discontinuity boundaries separating the phase plane into three disjoint regions with different dynamics. This type of system has wide applications in various subjects. As
Nanbin Cao, Yue Zhang, Xia Liu
doaj +1 more source
Applied Sciences, 2020 The main goal of any classification or regression task is to obtain a model that will generalize well on new, previously unseen data. Due to the recent rise of deep learning and many state-of-the-art results obtained with deep models, deep learning ...
Ivana Marin +2 more
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Deep Adversarial Reinforcement Learning With Noise Compensation by Autoencoder
IEEE Access, 2021 We present a new adversarial learning method for deep reinforcement learning (DRL). Based on this method, robust internal representation in a deep Q-network (DQN) was introduced by applying adversarial noise to disturb the DQN policy; however, it was ...
Kohei Ohashi +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Regular factors in regular graphs
Discrete Mathematics, 1993 The author shows that a \(k\)-regular \((k-1)\)-edge-connected graph with an even number of vertices has an \(m\)-factor not containing \(k-m\) arbitrarily prescribed edges whenever \(1\leq m\leq k-1\). This was known only for \(m=1\) or \(k-1\). Also the sharpness of this result and some corollaries are given.
openaire +3 more sources
Regularization and Model Selection with Categorial Effect Modifiers [PDF]
, 2010 The case of continuous effect modifiers in varying-coefficient models has been well investigated. Categorial effect modifiers, however, have been largely neglected.
Gertheiss, Jan, Tutz, Gerhard
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source