Results 121 to 130 of about 89,500 (309)
Floods and fish : recruitment and distribution of fish in the Volga River floodplain [PDF]
, 2010 Natural river floodplains are among the most diverse and productive ecosystems on Earth and provide key habitats for foraging, spawning and as a nursery for many riverine fish species.
Górski, K.
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Machine Learning Analysis of Hydrologic Exchange Flows and Transit Time Distributions in a Large Regulated River. [PDF]
Front Artif Intell, 2021 Ren H +4 more
europepmc +1 more source
NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Advanced Science, EarlyView.Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Advanced Science, EarlyView.We report a robust aerogel digital biosensor by integrating an enzyme‐mediated amorphous MOF within an aerogel matrix for on‐site pesticide detection. The enzyme‐mediated assembly strategy enables in situ tailoring of MOF into a porous amorphous structure, achieving both high stability and activity.
Changshun Su +7 more
wiley +1 more source
Climate change triggered planktonic cyanobacterial blooms in a regulated temperate river
Scientific ReportsHarmful algae blooms are a rare phenomenon in rivers but seem to increase with climate change and river regulation. To understand the controlling factors of cyanobacteria blooms that occurred between 2017 and 2020 over long stretches (> 250 km) of the ...
Julia Kleinteich +3 more
doaj +1 more source
Advanced Science, EarlyView.This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai +12 more
wiley +1 more source
Features of Zoobenthos Long-Term Dynamics in Regulated Area of Ob River [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2016 The abundance, biomass and taxonomic structure of dominant zoobenthos species in Novosibirsk reservoir have been analyzed for the entire period of the reservoir existence.
Liubov V. Yanygina
doaj
Advanced Science, EarlyView.Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
Surface water - groundwater interaction : hyporheic processes of a regulated river [PDF]
, 2012 During the last two decades large attention has been paid to the interface between rivers and groundwaters. Previous studies mainly focused on pristine streams with minimal human impact on the flow pattern (e.g (Triska et al., 1989).
Siergieiev, Dmytro,, Lundberg, Angela,
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