Results 161 to 170 of about 8,776,825 (339)

Chart Accompanying: An Assessment of Cross-National Regulatory Burden Comparisons [PDF]

open access: yes, 2006
The Article compares several rankings systems for national regulatory compliance costs. It finds the ranking systems are limited to differentiating between those countries least burdened by regulation from those most burdened by regulation.
Hopkins, Thomas D.
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Exploring the cancerous nexus: the pivotal and diverse roles of USP39 in cancer development

open access: yesDiscover Oncology
The ubiquitin–proteasome system enables post-transcriptional protein modification and is a major pathway for the degradation of most of them in eukaryotic cells.
Yujing Chen   +11 more
doaj   +1 more source

Pioneering Arterial Hypertension Phenotyping on Nationally Aggregated Electronic Health Records

open access: yesPharmacoepidemiology
Background: Hypertension is frequently studied in epidemiological studies that have been conducted using retrospective observational data, either as an outcome or a variable.
Jing Wei Neo   +15 more
doaj   +1 more source

When technology precedes regulation: the challenges and opportunities of e-pharmacy in low-income and middle-income countries [PDF]

open access: gold, 2021
Rosalind Miller   +17 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Infrastructure Investment in Network Industries: The Role of Incentive Regulation and Regulatory Independence [PDF]

open access: yes
This paper finds that coherent regulatory policies can boost investment in network industries of OECD economies. Rate-of-return regulation is generally thought to result in overinvestment, while incentive regulation is believed to entail underinvestment.
Balazs Egert
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Mechanism and Regulation of Gasdermin-Mediated Cell Death [PDF]

open access: bronze, 2019
Shiyu Xia, Louis Hollingsworth, Hao Wu
openalex   +1 more source

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