Results 221 to 230 of about 8,776,825 (339)

Resilience Factors and Their Association with Anxiety and Depressive Symptoms: An Intergenerational Perspective. [PDF]

Psychol Res Behav Manag
Drapisz A, Walfisch R, Shilton T, Hertz-Palmor N, Dekel I, Mosheva M, Gothelf D, Barzilay R.   +7 more
europepmc   +1 more source

Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle [PDF]

, 2014
Karen L. DeBalsi, Kari E. Wong, Timothy R. Koves, Dorothy H. Slentz, Sarah E. Seiler, April Wittmann, Olga Ilkayeva, Robert D. Stevens, Christopher G. R. Perry, Daniel S. Lark, Simon T. Hui, Luke I. Szweda, P. Darrell Neufer, Deborah M. Muoio   +13 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Does Coparenting Quality Mediate the Link Between Postpartum Parenting Stress and Perceptions of Emotion Regulation During Parenting? [PDF]

Fam Process
Finkelstein SD, Brock RL.
europepmc   +1 more source

Role of Ions in the Regulation of Light-Harvesting [PDF]

, 2016
Radek Kaňa, Govindjee Govindjee
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Safety of the extension of use of galacto-oligosaccharides as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Aguilera-Gómez M, Frenzel T, McArdle HJ, Moldeus P, Neuhäuser-Berthold M, Schlatter JR, van Loveren H, Turla E, Azzollini D, Hirsch-Ernst KI.   +24 more
europepmc   +1 more source

Wild-type p53 controls cell motility and invasion by dual regulation of MET expression

, 2011
Chang‐Il Hwang, Andrés Matoso, David C. Corney, Andrea Flesken‐Nikitin, Stefanie Körner, Wei Wang, Carla Boccaccio, Snorri S. Thorgeirsson, Paolo M. Comoglio, Heiko Hermeking, Alexander Yu. Nikitin   +10 more
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Effect of Emotional Labor on Young Nurses' Job Burnout: The Mediating Role of Social Support and Emotional Regulation. [PDF]

Nurs Open
Luo Y, Zhang Y, Chen J, Lu G, Liu J, Chen C.   +5 more
europepmc   +1 more source