Results 101 to 110 of about 803,735 (263)

Ethics consultation for integrating ethics in technology readiness levels (TRL)

open access: yesJournal of Responsible Innovation
Integrating ethics aims at an ethical co-design of technology by focusing on socio-technical contexts and establishing ethical perspectives in development processes.
Lena Fiedler   +2 more
doaj   +1 more source

The Ethics of Food Production and Regulation of “Misbranding” [PDF]

open access: yes, 2012
As consumers have become more conscious of the ethical implications of food choices, the food industry has capitalized on our concern by introducing labels that appeal to our moral sensibilities. Labels such as “free range” and “cage free” influence the
Hoffman, Selena
core  

Voluntary measures, participation and fundamental rights in the governance of research and innovation [PDF]

open access: yes, 2018
open1noResponsible Research and Innovation (RRI) aims at being a new governance paradigm aiming at steering the innovation process in a participative manner by constructing responsibility as a shared process between innovators and societal stakeholders ...

core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Ethics that Fails to Regulate War, Ethics that Enhances War

open access: yesJournal of Bioethical Inquiry
Abstract This short perspective piece argues that wars are often conducted in settings where ethical injunctions are ignored or overridden and where ethical oversight is avoided or circumvented. This is particularly the case with intrastate conflicts and is exacerbated by novel military technologies.
Alphonso Lingis, Paul Komesaroff
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Ethics and self-regulation in the training of education professionals

open access: yesIXTLI, 2016
Book Review Ethics and self-regulation in the training of education professionals, coordinated by Juan Martin Lopez Calva and Martha Leticia Gonzalez Gaeta.
Martha de Jesús Portilla León
doaj  

Regulation (EU) 536/2014 and the role of ethics committees: a proposal for a review system model

open access: yesBMJ Open
Independent ethics committees play an important role in clinical trials as well as in all health-related research. Internationally, the national laws of the individual countries have guided their local development and organisation over the decades ...
Carlo Petrini, Luciana Riva
doaj   +1 more source

On Understanding the Human Nature of Good and Bad Behavior in Business: A Behavioral Ethics Approach [PDF]

open access: yes, 2009
The numerous scandals in business, such as those at AIG, Tyco, WorldCom, Enron and Ahold, have made all of us concerned about the emergence of unethical and irresponsible behavior in organizations. Such widespread corruption in business and politics has,
Cremer, D. (David) de
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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