Results 51 to 60 of about 803,735 (263)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Regulation of Sexual Harassment in the Academic Environment

open access: yesAnnales, Series Historia et Sociologia
This article analyses the regulation of sexual harassment within the academic environment. It highlights that sexual harassment is addressed not only by legal regulations but also through codes of ethics.
Katja Filipčič, Manja Skočir
doaj   +1 more source

Clinical ethics consultation among Italian ethics committee: A mixed method study.

open access: yesPLoS ONE, 2019
ObjectiveThe general purpose for ethics consultations is to deliberate on issues on medical and scientific research and act towards the safeguard of the patient's rights and dignity.
Ludovica De Panfilis   +5 more
doaj   +1 more source

Society-in-the-Loop: Programming the Algorithmic Social Contract

open access: yes, 2017
Recent rapid advances in Artificial Intelligence (AI) and Machine Learning have raised many questions about the regulatory and governance mechanisms for autonomous machines.
Rahwan, Iyad
core   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Sur la régulation institutionnelle de l’éthique en recherche

open access: yesSociologies, 2020
Institutional regulation of research ethics raises a number of difficult issues, especially for the social sciences. The article begins with a review of the main criticisms.
Éric Gagnon
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Virtue, well-being, and mentalized affectivity

open access: yesResearch in Psychotherapy
Virtue ethics, featuring the claim that virtue leads to wellbeing, has been imported by psychologists from philosophy. In the first part of the paper, we re-examine the source of virtue ethics in Aristotle’s philosophy and question whether virtues can ...
Elliot Jurist   +4 more
doaj   +1 more source

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