Results 91 to 100 of about 2,720,747 (207)

Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss

npj Aging and Mechanisms of Disease, 2020
Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pathogenesis of
Tetsuya Oishi, Daisuke Matsumaru, Nao Ota, Hiroshi Kitamura, Tianxiang Zhang, Yohei Honkura, Yukio Katori, Hozumi Motohashi   +7 more
doaj   +1 more source

Hypoxia and the regulation of gene expression

Molecular Medicine Today, 1998
The optimal delivery of oxygen to tissues is essential both to ensure adequate energy provision and to avoid the toxic effects of higher oxygen concentrations. For this to occur, organisms must be able to sense oxygen and respond to changes in oxygen tension by altering gene expression.
Gleadle, J, Ratcliffe, P
openaire   +2 more sources

Six Highly Conserved Targets of RNAi Revealed in HIV-1-Infected Patients from Russia Are Also Present in Many HIV-1 Strains Worldwide

Molecular Therapy: Nucleic Acids, 2017
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets.
Olga V. Kretova, Daria M. Fedoseeva, Maria A. Gorbacheva, Natalya M. Gashnikova, Maria P. Gashnikova, Nataliya V. Melnikova, Vladimir R. Chechetkin, Yuri V. Kravatsky, Nickolai A. Tchurikov   +8 more
doaj   +1 more source

Author Correction: Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

Nature Communications, 2022
Federico Pelisch, Remi Sonneville, Ehsan Pourkarimi, Ana Agostinho, J. Julian Blow, Anton Gartner, Ronald T. Hay   +6 more
doaj   +1 more source

Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC

eLife, 2018
We describe Ribo Mega-SEC, a powerful approach for the separation and biochemical analysis of mammalian polysomes and ribosomal subunits using Size Exclusion Chromatography and uHPLC.
Harunori Yoshikawa, Mark Larance, Dylan J Harney, Ramasubramanian Sundaramoorthy, Tony Ly, Tom Owen-Hughes, Angus I Lamond   +6 more
doaj   +1 more source

Transcriptional Regulation of Gene Expression in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]

, 1990
The only well-characterized study of gene expression in Tetrahymena thermophila (1) demonstrates that the temperature dependent expression of the Ser H3 gene is regulated at the level of mRNA stability.
Gorovsky, Martin A., Karrer, Kathleen M., Stargell, Laurie A.   +2 more
core   +1 more source

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

Nature Communications, 2018
Chromosome segregation and genome maintenance require the removal of DNA bridges that link chromosomes just before cells divide. Here the authors show that the LEM-3/Ankle1 nuclease processes DNA bridges before cells divide and define a previously ...
Ye Hong, Remi Sonneville, Bin Wang, Viktor Scheidt, Bettina Meier, Alexander Woglar, Sarah Demetriou, Karim Labib, Verena Jantsch, Anton Gartner   +9 more
doaj   +1 more source

Autogenous regulation of gene expression [PDF]

Journal of Bacteriology, 1993
S, Maloy, V, Stewart
openaire   +2 more sources

Regulation of Gene Expression in Cancer-An Overview. [PDF]

Cells, 2022
Ferlier T, Coulouarn C.
europepmc   +1 more source

Epigenetic regulation of gene expression in rare inherited retinal disorders. [PDF]

Front Genet
Menna F, De Luca L, Meduri A, Baldascino A, Lupo S, Vingolo EM.   +5 more
europepmc   +1 more source