YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Early Behavioral Inhibition and Emotion Regulation: Pathways Toward Social Competence in Middle Childhood [PDF]
, 2015 Elizabeth C. Penela +4 more
openalex +1 more source
miRNA repertoire and host immune factor regulation upon avian coronavirus infection in eggs [PDF]
, 2020 Vera Kemp +5 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Regulation of markers of synaptic function in mouse models of depression: chronic mild stress and decreased expression of VGLUT1 [PDF]
, 2010 N. Elizalde +9 more
openalex +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Exception from Informed Consent in Emergency Care Research: Reports from a Workshop Addressing "Edge Cases". [PDF]
Ethics Hum ResBrown J, Dickert NW, Silbergleit R.
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Comparative Chart of “Right-to-Ask” Laws in the U.S. and Abroad [PDF]
, 2006 Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
Capital regulations: the road ahead [PDF]
This paper was presented at the conference "Financial services at the crossroads: capital regulation in the twenty-first century" as part of session 7, "The future of capital regulation." The conference, held at the Federal Reserve Bank of New York on ...
Tom de Swaan
core