Animal rabies prevention and control in Shanghai, China: policies and practices, 2011-2025. [PDF]
Zhu T +11 more
europepmc +1 more source
The Life-Cycle and Character of Crypto-Assets: A Framework for Regulation and Investor Protection
Brianne Smith
openalex +2 more sources
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Hygiene knowledge and practices in the Lagos wild meat value chain: Cultural influences, regulatory gaps, and infrastructure needs. [PDF]
Akpan SN +10 more
europepmc +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
An outline of the 2006 Pupil Registration Regulations and the changes from the 1995 Pupil Registration Regulations [PDF]
core
Fifty shades of pregnancy warning labels on wine bottles: An observational study in France. [PDF]
Droulers O, Lacoste-Badie S.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The practice of drug emergency supply in China during the COVID-19 pandemic: A policy mix perspective. [PDF]
Jie-Ying Z +7 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source

