Results 361 to 370 of about 6,497,314 (414)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Ethical and legal considerations in healthcare AI: innovation and policy for safe and fair use. [PDF]

R Soc Open Sci
Pham T.
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

From Command-Control to Lifecycle Regulation: Balancing Innovation and Safety in China's Pharmaceutical Legislation. [PDF]

Healthcare (Basel)
Zhang J, Tang S, Sun P.
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Asilomar Goes Underground: The Long Legacy of Recombinant DNA Hazard Debates for the Greater Boston Area Biotechnology Industry. [PDF]

J Hist Biol
Scheffler RW.
europepmc   +1 more source

GCSE controlled assessment regulations for English [PDF]

, 2009

core  

Noble Humbug? Hard and soft laws on clinical placebo use. [PDF]

Front Psychol
Richard M, Ganz M, Hornstein LD, Stehlik B, Levy M, Blease CR, Annoni M, Elger BS, Gaab J.   +8 more
europepmc   +1 more source

The school premises (England) regulations 2012 [PDF]

, 2012

core  

Evaluating the Proportion of Foods and Beverages in the Canadian Grocery and Chain Restaurant Food Supply That Would Be Restricted from Marketing to Children on Television and Digital Media. [PDF]

Nutrients
Jeong H, Mulligan C, Khan A, Vergeer L, L'Abbe MR.   +4 more
europepmc   +1 more source