Results 121 to 130 of about 1,936,993 (306)
IRBIT a Master Regulator of Cell Physiology [PDF]
, 2017 (excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G +2 more
core +1 more source
Infinitely many regulator fields for chiral fermions
, 1992 We show that two recent independent proposals for regularizing a chiral gauge theory stem from one common trick. If the anomaly free complex representation carried by the right handed fermi--fields is $r$ one constructs a vector like theory with flavored
Bodwin +25 more
core +2 more sources
Journal of Experimental Medicine, 2009 Co-culture of PD-L1–expressing beads (red) and naive T cells (purple) promotes their conversion into T reg cells (green).
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Dynamic Regulation Design Without Payments: Timing is Everything [PDF]
We consider a two period model of optimal regulation of a firm subject to marginal compliance cost shocks. The regulator faces an asymmetric information problem: the firm knows current compliance costs, but the regulator does not.
David L. Kelly, Ralph Boleslavsky
core
Increasing efficiency of switching type regulator circuits Patent [PDF]
, 1968 Switching series regulator with gating control ...
Clapp, W. M.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
MODIFIKASI DAN APLIKASI POWER WINDOW PADA TOYOTA HIACE [PDF]
, 2011 Tujuan Proyek Akhir ini adalah: (1) Dapat merancang power window tipe silang pada Toyota Hiace. (2) Dapat memodifikasi dan aplikasi power window tipe silang pada Toyota Hiace (3) Untuk mengetahui kinerja power window apakah dapat bekerja dengan baik ...
ASEP, TRIANTO
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source