Results 211 to 220 of about 2,668,555 (395)

The lysosomal catabolism of nucleic acids—critical regulators of the innate immune system

Cedric Cappel, Markus Daμμe
openalex   +1 more source

Tanycytes As Regulators of Seasonal Cycles in Neuroendocrine Function [PDF]

, 2017
Jo E. Lewis, Francis J. P. Ebling
openalex   +1 more source

Systematic evaluation of pigment-based whole-cell lead biosensors: challenges in genetic circuit engineering and critical considerations for background noise control. [PDF]

Front Bioeng Biotechnol
Guo Y, Deng LD, Gong WW, Zhang J, Hui CY.   +4 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Policy Framework and Barriers in Antimicrobial Consumption Monitoring at the National Level: A Qualitative Study from Pakistan. [PDF]

Antibiotics (Basel)
Ihsan B, Iqbal SM, Aufy M, Jamil Q.
europepmc   +1 more source

TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

Cell, 2006
K. Bensaad, A. Tsuruta, M. Selak, M. N. C. Vidal, K. Nakano, R. Bartrons, E. Gottlieb, K. Vousden   +7 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Designing modular genetic sensors with TtgR/AcrR family transcriptional regulators by using a statistical and data-driven approach. [PDF]

Nucleic Acids Res
Budhathoki A, Kinshuk S, Nguyen N, Chan CTY.   +3 more
europepmc   +1 more source

IL-10: The Master Regulator of Immunity to Infection

Journal of Immunology, 2008
Kevin N. Couper, D. Blount, E. Riley
semanticscholar   +1 more source