Results 221 to 230 of about 2,668,555 (395)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A large reverse-genetic screen identifies numerous regulators of testis nascent myotube collective cell migration and collective organ sculpting.

Maik C. Bischoff, Jenevieve E. Norton, Erika A. Munguia, Sarah E. Clark, Noah J. Gurley, Rebecca Korankye, Emmanuel Addai Gyabaah, Taino Encarnacion, Christopher J. Serody, Corbin D. Jones, Mark Peifer   +10 more
openalex   +1 more source

Optimizing a Buck Voltage Regulator and the Number of Decoupling Capacitors for a PDN Application

, 2021
Aurea E. Moreno-Mojica, José E. Rayas‐Sánchez, Felipe J. Leal-Romo   +2 more
openalex   +2 more sources

The PhoPQ two-component regulatory system as an important regulator of bacterial stress response. [PDF]

Mol Biol Rep
Omelaniuk AM, Gmiter D, Kaca W.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Co‐ordinated regulation of two divergent promoters through higher‐order complex formation by the LysR‐type regulator ThnR [PDF]

, 2009
Aroa López‐Sánchez, Elena Rivas‐Marín, Olga Martínez‐Pérez, Belén Floriano, Eduardo Santero   +4 more
openalex   +1 more source

A network-based model of Aspergillus fumigatus elucidates regulators of development and defensive natural products of an opportunistic pathogen. [PDF]

Nucleic Acids Res
Carriel CC, Halberg-Spencer SA, Kotvanova M, Pyne S, Park SC, Seo HW, Schmidt A, Calise DG, Ané JM, Keller NP, Roy S.   +10 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Green synthesized nanoparticles outperform conventional plant growth regulator application in enhancing lupine yield productivity and nutritional quality

Mohamed Osman, Samha Dowidar, A. El-Sheikha, Gehad A. Ragab   +3 more
openalex   +1 more source

Effect of different plant growth regulators on callus induction in Catalpa bungei [PDF]

, 2010
Juan Lin, Lihua Wu, Liang Jing, Junhui Wang   +3 more
openalex   +1 more source