Precise Transcription Control Drives Optimized Catabolism of β-5-Type Lignin-Derived Dimers in <i>Sphingobium lignivorans</i> SYK-6. [PDF]
Kawazoe M +5 more
europepmc +1 more source
Isolation of Helminthosporol as a Natural Plant Growth-regulator and its Chemical Structure
Saburo Tamura +3 more
openalex +2 more sources
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Impact of intestinal bacteria on biofilm formation, motility, virulence, and gene expression in <i>Vibrio parahaemolyticus</i>. [PDF]
Huang Q +7 more
europepmc +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Preexisting Genetic Background Primes the Responses of Human Neurons to Amyloid β. [PDF]
Soladogun AS, Zhang L.
europepmc +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Unraveling the signaling pathways of plant cold stress: current insights and future directions. [PDF]
Peng C, Hua W, Liu J.
europepmc +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Correction: Regulator of G protein signaling-1 facilitates ovarian cancer development by modulating NF-kB signal pathway. [PDF]
Shengnan L +5 more
europepmc +1 more source

