Results 261 to 270 of about 1,489,667 (310)

Exploring the roles of conserved context-dependent cis-regulatory elements (cdCREs) in multicellularity, human health and disease. [PDF]

FEBS J
McEwan A, Rattray A, Hutchings G, Hay E, Murgatroyd C, MacKenzie A.   +5 more
europepmc   +1 more source

Conservation of regulatory elements with highly diverged sequences across large evolutionary distances. [PDF]

Nat Genet
Phan MHQ, Zehnder T, Puntieri F, Magg A, Majchrzycka B, Antonović M, Wieler H, Lo BW, Baranasic D, Lenhard B, Müller F, Vingron M, Ibrahim DM.   +12 more
europepmc   +1 more source

Epigenomic signatures of cis-regulatory elements in the developing mouse and pig forelimb. [PDF]

Sci Data
Sospedra-Arrufat I, Martínez-García PM, Gil-Gálvez A, Alcaina-Caro A, Tena JJ, Nusspaumer G, Lopez-Rios J.   +6 more
europepmc   +1 more source

Predictable Engineering of Signal-Dependent Cis-Regulatory Elements

Cornwall-Scoones J, Benzinger D, Yu T, Pezzotta A, Sagner A, Gerontogianni L, Bernadet S, Finnie E, Boezio GLM, Stuart HT, Melchionda M, Inge OCK, Dumitrascu B, Briscoe J, Delás MJ.   +14 more
europepmc   +1 more source

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Mapping regulatory elements

Nature Biotechnology, 2016
Regulatory genomic elements can now be studied in their native context using two CRISPR-based high-throughput approaches.
Yuexin, Zhou, Wensheng, Wei
openaire   +2 more sources

Erythroid regulatory elements

STEM CELLS, 1993
Erythroid differentiation leads to the production of red blood cells that contain a high level of hemoglobin. This level is mainly regulated by globin gene transcription during development and differentiation. Although numerous cis-acting sequences are involved in transcriptional activity of globin genes, combinations of three motifs, CCACC, SP1 and ...
N, Raich, P H, Romeo
openaire   +2 more sources

Regulatory elements in aflatoxin biosynthesis

Mycotoxin Research, 2006
This review provides a synopsis of factors involved in the regulation of aflatoxin inAspergillus species at the molecular level. Much of the knowledge available today on the regulation of secondary metabolite production in fungi has been gleaned from studies of the aflatoxin gene cluster inA. flavus andA.
J W, Cary, K C, Ehrlich, S P, Kale, A M, Calvo, D, Bhatnagar, T E, Cleveland   +5 more
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Toward a comprehensive catalog of regulatory elements

Human Genetics, 2023
Regulatory elements are the genomic regions that interact with transcription factors to control cell-type-specific gene expression in different cellular environments. A precise and complete catalog of functional elements encoded by the human genome is key to understanding mammalian gene regulation.
Kaili Fan, Edith Pfister, Zhiping Weng
openaire   +3 more sources

Regulatory elements in the KlHEM1 promoter

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2008
In Kluyveromyces lactis the gene encoding 5-aminolevulinate synthase, KlHEM1, is regulated at the transcriptional level by carbon source and oxygen availability. The KlHEM1 promoter, fused to the reporter lacZ gene, has been analysed by deletion and direct mutagenesis techniques in order to find regulatory elements functionally relevant in this ...
Laura, Núñez, Ana, Rodríguez-Torres, María Esperanza, Cerdán   +2 more
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Conserved regulatory elements in AMPK

Nature, 2013
arising from B. Xiao et al. , 230–233 (2011)10.1038/nature09932 The AMP-activated protein kinase (AMPK), an αβγ heterotrimeric enzyme, has a central role in regulating cellular metabolism and energy homeostasis1.
Chen, Lei, Xin, Feng-Jiao, Wang, Jue, Hu, Jicheng, Zhang, Yuan-Yuan, Wan, Shuo, Cao, Lu-Sha, Lu, Chang, Li, Peng, Yan, S. Frank, Neumann, Dietbert, Schlattner, Uwe, Xia, Bin, Wang, Zhi-Xin, Wu, Jia-Wei   +14 more
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