Results 121 to 130 of about 2,089,915 (236)

Autistic matrescence as dynamic person-environment fit: a theoretical model of regulatory resources and support usability

Acta Psychologica
Background: Matrescence is a developmental transition involving bodily, psychological, relational, and social change. Research on autistic pregnancy and early parenthood documents sensory overload, communication barriers, disrupted routines, professional
Pia-Cecilia Steinbrück
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Study on experience and mechanism of regulatory fit in research resilience among academic nursing doctoral students

Huli yanjiu
ObjectiveTo explore the influencing mechanism of research resilience among academic nursing doctoral students.MethodsA multi⁃center purposive sampling method was adopted.In June 2026,a total of 19 nursing doctoral students from multiple universities in ...
JIN Ji, ZHANG Linghui, HUAI Panpan
doaj  

Unlocking flow in the gig economy: A configurational study based on an integrated JD-R and regulatory fit perspective

Acta Psychologica
Research by platform management and academic scholars on how to improve the flow experience for platform workers has yet to yield clear conclusions. By integrating the Job Demands-Resources (JD-R) model with Regulatory Fit Theory, this study develops a ...
Jing Xiu, Qian Li, Xiaoqian Zu, Qianqian Zhang   +3 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Can regulatory fit improve performance? Effect of types of regulatory fit and performance

The Japanese journal of psychology, 2017
Miki Toyama, Masato Nagamine, Li Tang, Shuhei Miwa, Ryo Kurozumi, Atsusi Aikawa   +5 more
openaire   +2 more sources

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source